Dynamics of Wound Healing in Patients With Obesity (NCT07756112)
Temporal Dynamics of Palatal Wound Healing With and Without Adjunctive Biologics in Patients With Obesity
🩺 Plain-English Summary (8th-Grade Level)
Healing after dental surgery can vary from person to person. This study is being done to understand how body weight (obesity vs. normal weight) may affect healing after tissue is removed from the roof of the mouth during a gum graft procedure. The study will also evaluate whether a healing material made from a participant's own blood, called platelet-rich fibrin (PRF), is comparable in quantity and quality to the standard-of-care collagen plug. First, participants will be classified into obese or normal weight groups. Next, participants will be randomized to receive either collagen plug or platelet-rich fibrin clot during their surgical procedure Then, participants will return for 4 visits up to 30 days from the surgery visit.
Who can join: Review the eligibility criteria below.
Location: University of Iowa College of Dentistry and Dental Clinics — Iowa City, Iowa
Age range: 18 Years to 70 Years
🧪 Interventions in This Study
- Collagen Plug (standard of care) (PROCEDURE)
- Platelet-Rich Fibrin Clot (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Iowa College of Dentistry and Dental Clinics — Iowa City, Iowa
📞 Contact the Study Coordinator
Phone: (319) 467-1475
Email: sukirth-ganesan@uiowa.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.