๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-13

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight (NCT07770841)

Efficacy and Safety of Once Daily Oral Semaglutide in Adults With Overweight or Obesity

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Novo Nordisk A/S

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to see how oral semaglutide, when taken in lower doses help lowering of body weight in participants with excess body weight when compared to 'dummy' tablets (placebo). Results from this study will help select the most optimal lower dose of oral semaglutide that can be used for treating participants living with overweight or obesity.

Who can join: Review the eligibility criteria below.

Location: Uni of Alabama at Birmingham โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (62 Sites)

Showing the first 25 of 62 sites.

  • Uni of Alabama at Birmingham โ€” Birmingham, Alabama
  • Headlands Research California, LLC โ€” Escondido, California
  • National Research Institute - Huntington Park โ€” Huntington Park, California
  • Los Angeles Institute for Metabolic Research โ€” Los Angeles, California
  • ERG Holding Company, LLC / Evolution Research Group, LLC โ€” Delray Beach, Florida
  • ERG Holding Company, LLC / Evolution Research Group, LLC โ€” Fort Myers, Florida
  • Jedidiah Clinical Research โ€” Tampa, Florida
  • East West Med Res Inst โ€” Honolulu, Hawaii
  • L-MARC Research Center โ€” Louisville, Kentucky
  • StudyMetrix Research LLC โ€” City of Saint Peters, Missouri
  • Jubilee Clinical Research, Inc. โ€” Las Vegas, Nevada
  • Corvallis Clinic PC Clinical Research Department โ€” Corvallis, Oregon
  • UPA Ctr Weight and Eating Dis โ€” Philadelphia, Pennsylvania
  • Spartanburg Medical Research โ€” Spartanburg, South Carolina
  • Cedar Health Research โ€” Dallas, Texas
  • Selma Medical Associates โ€” Winchester, Virginia
  • Anima Research Center โ€” Alken,
  • Imelda โ€” Bonheiden,
  • UZ Brussel - Universitair Ziekenhuis Brussel โ€” Brussels,
  • Universitair Ziekenhuis Gent โ€” Ghent,
  • KORMONT โ€” Kluisbergen,
  • AIPSMC - DiMed EOOD โ€” Haskovo,
  • Medical Center Zdrave Lom EOOD โ€” Lom,
  • IPMC - Dr. Elizabeta Dimitrova โ€” Petrich,
  • MHAT Hadzhi Dimitar OOD โ€” Sliven,

๐Ÿ“ž Contact the Study Coordinator

Phone: (866) 867-7178

Email: clinicaltrials@novonordisk.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Overweight clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—