100 Recruiting Studies at Cleveland Clinic
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Cleveland, Ohio
All research centersRecruiting Studies at Cleveland Clinic
🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)
Atrial Fibrillation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Phase-Aligned Atrial Fibrillation Mapping
Atrial Fibrillation (AF)
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral Head
Avascular Necrosis
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers
Bertolotti's Syndrome
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Real World Treatment Experience of Patients With Breast, Lung, or GI Cancer or Multiple Myeloma Using Remote Symptom Monitoring
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
CARNIVAL Study: Gut Flora Dependent Metabolism of Dietary CARNItine and Phosphatidylcholine and cardioVAscuLar Disease
Dietary Modification
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Impact of Surgical Coaching on Resident ObGyn Laparoscopic Skills
Educational Problems
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy)
Epilepsy
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Neuromodulation With Percutaneous Electrical Nerve Field Stimulation
Gastroparesis Like Symptoms
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip
Heart Failure
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Cleveland Heart and Metabolic Prevention Study
Heart Failure Risk Factors in Healthy Individuals
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)
High Intensity Exercise
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Gluten Free Diet in Hashimoto's Hypothyroidism
Hypothyroidism
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease
IBD
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy
Lifestyle
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Sequential Hypo- and Normo-thermic Perfusion to Preserve Extended Criteria Donor Livers for Transplantation
Liver Transplantation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Multidisciplinary Lifestyle Interventions for Neurological Disorders During the Silent Phase
Neurological Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
Sequential or CombinaTion Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)
Obesity
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Analysis of a Stepped-Wedge Implementation of the PT-PENCIL Tool
Physical Therapy Evaluation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Continuous Glucose Monitoring in Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome (PCOS)
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Uterine Transplantation for the Treatment of Uterine Factor Infertility
Primary Uterine Infertility
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Variation in Humeral Head Bone Marrow Characteristics With Rotator Cuff Repair Healing
Rotator Cuff Tears
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Operating Room Air Filtration/Sterilization
Surgery
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
Thyroid Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Randomized Controlled Trial of Digital Twin Precision Treatment: A Novel Whole Body Digital Twin Enabled Precision Treatment for Type 2 Diabetes
Type 2 Diabetes
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer
Urothelial Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Oral Sodium to Preserve Renal EfficiencY in Acute Heart Failure
Volume Overload
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Life Expectancy-informed Colorectal Cancer Screening
Colorectal Cancer Control and Prevention
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
COPD
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Whole Gut Motility Abnormalities Following GLP-1 Receptor Agonist (GLP-1RA) Initiation
Diabetes
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Antireflux Surgery Without Preoperative Esophageal Manometry
GERD
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
Heart Failure (HF)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Clinical Decision Support Tool for the Treatment of Uncontrolled Hypertension
Hypertension
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic
A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MS
Multiple Sclerosis (MS) - Relapsing-remitting
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
Parkinson Disease
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Imaging in Semaglutide Study
Type 2 Diabetes
View Study & Checklist ➔ 🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849
Advanced Solid Tumor
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
Afib
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
HA35 Moderate Alcoholic Hepatitis (AH) Study
Alcoholic Hepatitis
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Ethanol Induces Skeletal Muscle Autophagy
Alcoholic Liver Disease
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
Amblyopia
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue
Aortic Aneurysm
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease
Aortic Regurgitation
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
Atrial Fibrillation
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Intracardiac Echocardiography Guided Watchman Device Implant
Atrial Fibrillation
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Metabolic Impacts of Ren-Nu: A Dietary Program for Polycystic Kidney Disease
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Imaging Assessments of ARPKD Kidney Disease Progression
Autosomal Recessive Polycystic Kidney Disease
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of the Prostate
Benign Prostatic Hyperplasia With Outflow Obstruction
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Longitudinal Validation of CIRC Technologies
Cardiovascular Diseases
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Vascular Lab Resource (VLR) Biorepository
Cardiovascular Diseases
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Mesh Removal Versus No Mesh Removal for Chronic Groin Pain After Inguinal Hernia Repair
Chronic Groin Pain
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease
Chronic Kidney Disease(CKD)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis
Cirrhosis, Liver
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Molecular Mechanism of Exercise in Cirrhosis
Cirrhosis, Liver
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Effects of Non-invasive Brain Stimulation on Pain Avoidance Behavior in Chronic Pain Patients
Complex Regional Pain Syndrome (CRPS)
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Remote Monitoring in Pregnant Women With Congenital Heart Disease Using Wrist Wearables
Congenital Heart Disease
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
A Registry of Cardiac PET and CardioFlux Magnetocardiography in Patients With Suspected Coronary Ischemia.
Coronary; Ischemic
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Ultrasound-Guided Versus Standard Margin Selection in Ileocecal Resection of Terminal Ileal CD
Crohn's Disease (CD)
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Topical Ruxolitinib Cream for Refractory Cutaneous Dermatomyositis
Dermatomyositis
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Gut Flora Metabolite Reduction After Dietary Intervention (GRADY)
Dietary Modification
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Uterine Manipulation During Minimally Invasive Surgery for Early Stage Endometrial Cancer
ENDOMETRIAL CANCER
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Healthy Aging in People With Epilepsy Program
Epilepsy
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Readiness Brain Operation Optimization Training (ReBOOT) for Epilepsy Surgery
Epilepsy
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Bridging the Gap: Educating Patients on Social Determinants of Health to Improve Epilepsy Surgery Access and Outcomes
Epilepsy
View Study & Checklist ➔ 🟢 Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic
Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy
Esophageal Cancer Surgery
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor
Essential Tremor
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
GLP - 1
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Normal Donor Blood Draws for Platelet Studies and Biomarker Evaluation (ND-PLT)
Healthy
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
HA35 Acute Alcohol Study
Healthy Controls
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Evaluation of Cochlear (Promontory) Stimulation During Awake Ear Surgery (TONES Study)
Hearing Disorder
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
Heart Failure
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"
Heart Failure
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Wearable Technology in Heart Failure Patients
Heart Failure
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Everglade Stem, World Cup and World Liner Post Market Clinical Follow-up
Hip Disease
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Spartan Stem, World Cup and World Liner Post Market Clinical Follow-up Study
Hip Replacement
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
Hypertension
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic
Hypertension (HTN)
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
A Cardiac Disease Quality of Life Study
Hypertrophic Obstructive Cardiomyopathy
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Physician Modified Endovascular Grafts for the Treatment of Juxtarenal Aortic Aneurysms
Juxtarenal Aortic Aneurysm
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
Kidney Stone
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Biliary Anastomosis in Living Donor Liver Transplant With Amniotic Tissue
Liver Transplant
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)
Morbid Obesity
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
The Management of Necrotizing Soft Tissue Infection Wounds With Cytal® Wound Matrix and MicroMatrix®
Necrotizing Fascitis
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Phenotypic Classification of FMR With CMR
Nonischemic Congestive Cardiomyopathy
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms
Overactive Bladder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease
Parkinson Disease
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
Parkinson Disease
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Personalized Real-Time DBS and PD Mechanisms
Parkinson Disease
View Study & Checklist ➔ 🟢 Recruiting Phase2 🧠 Behavioral & Psychological Program
Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS
Parkinson's Disease
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Health-Related Quality of Life and Metabolic Outcomes in PCOS
PCOS (Polycystic Ovary Syndrome)
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Centered Surgery - Preoperative Counseling and Patient Satisfaction
Pelvic Organ Prolapse
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon
Polyps Colorectal
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study
Post Operative Pain
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy
Post Operative Pain
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Zimmer ActivBraid Rotator Cuff Repair (RCR) Study
Rotator Cuff Repair of the Shoulder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Virtual Patient Groups for Sarcoidosis Associated Fatigue
Sarcoidosis
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Early Versus Late Adjunctive Vasopressin in Septic Shock
Sepsis
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution
ST Elevation Myocardial Infarction
View Study & Checklist ➔