58 Recruiting Studies at Houston Methodist Hospital

Active clinical trials at this research center, sourced directly from the NIH registry.

📍 Houston, Texas

All research centers

Recruiting Studies at Houston Methodist Hospital

🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Multi-virus CTLs Expressing CD19 Chimeric Receptors, CD19 Positive Malignancies Post SCT, MULTIPRAT

Acute Lymphoblastic Leukemia (ALL)

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Acute Lymphoblastic Leukemia in Remission

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLL

B Cell Lymphoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

T Cells Expressing HER2-specific Chimeric Antigen Receptors(CAR) for Patients With HER2-Positive CNS Tumors

Brain Tumor, Recurrent

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Neoadjuvant Atezolizumab in Cutaneous Melanoma

Cutaneous Melanoma

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

ORIF Distal Radius Blood Flow Restriction Therapy

Distal Radius Fractures

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas

Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Most Closely Matched 3rd Party Rapidly Generated LMP, BARF1 And EBNA1 Specific CTL, EBV-Positive Lymphoma (MABEL)

Hodgkin Disease

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Administration of TAA-Specific CTLs; Hodgkin or Non-Hodgkin Lymphoma; TACTAL

Hodgkin Lymphoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

EBV CTLs Expressing CD30 Chimeric Receptors For CD 30+ Lymphoma

Hodgkin's Lymphoma

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🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery

Limb Occlusion Pressure

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🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol

Interleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in Autologous T Cells for Solid Tumors

Liver Cell Carcinoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL

Lymphoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Autologous/Allogeneic TGFbeta-resistant LMP-specific CTL, Lymphoma (TGF-beta)

Lymphoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAIN

Neuroblastoma

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🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol

Activated T Lymphocytes Expressing CARs, Relapsed CD19+ Malignancies Post-Allo HSCT(CARPASCIO)

Non-Hodgkin's Lymphoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma

Osteosarcoma

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🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Refractory B-Cell Non-Hodgkin Lymphoma

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🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

Relapsed Neuroblastoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer

Resectable Hepatocellular Carcinoma

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🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic

Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma

Sarcoma

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🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic

IO Vancomycin in TSA

Shoulder Injuries

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🔵 Active, Not Recruiting Phase1 📋 Clinical Research Protocol

Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells

T-cell Acute Lymphoblastic Lymphoma

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🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic

Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer

Urothelial Carcinoma Bladder

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers

Advanced Small Intestine Cancer

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🟡 Not Yet Recruiting Phase1 📋 Clinical Research Protocol

TRAIL-R2 and HER2 Bi-Specific Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Metastatic Breast Cancer

Breast Cancer

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🟡 Not Yet Recruiting Phase1 💊 Investigational Drug / Biologic

Autologous IC-Nine, CD30 CAR, and Constitutive IL7R Expressing EBVST for CD30 Lymphoma (ANCILE-30)

Diffuse Large B-Cell Lymphoma (DLBCL)

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🟡 Not Yet Recruiting Phase2 / Phase3 💊 Investigational Drug / Biologic

IO Vancomycin Spine

Lumbar Fusion Surgery

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Effect of BFR Rehab After Achilles Tendon Rupture

Achilles Tendon Rupture

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Anterior Cruciate Ligament (ACL) Reconstruction With Autologous Fat Pad Derived Mesenchymal Stem Cells

Anterior Cruciate Ligament Reconstruction

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

DeBakey Cardiovascular Magnetic Resonance Study

Cardiovascular Diseases

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

CD30-Positive Diffuse Large B-Cell Lymphoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Clazakizumab vs. Placebo - COVID-19 Infection

COVID-19 Infection

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🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program

VoiceLove Digital Therapy for Delirium in the ICU

Delirium

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🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

Home Tele Rehabilitation Therapy for Vascular Dementia

Dementia, Vascular

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🟢 Recruiting Phase3 🩺 Clinical Procedure Protocol

Sentinel Node Biopsy in Endometrial Cancer

Endometrial Cancer Stage I

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

Endoscopic Sleeve Gastroplasty

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Blood Flow Restriction (BFR) Training on the Ulnar Collateral Ligament (UCL)

Healthy

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🟢 Recruiting Phase1 📋 Clinical Research Protocol

Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells

Hepatoblastoma

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Phase II High Risk Prostate Cancer Trial Using Gene & Androgen Deprivation Therapies, Radiotherapy, & Surgery

High-risk Prostate Cancer

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🟢 Recruiting Phase1 📋 Clinical Research Protocol

CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

Hodgkin's Lymphoma

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🟢 Recruiting Phase4 💊 Investigational Drug / Biologic

Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty

Infections

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS

Neurogenic Bladder

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🟢 Recruiting Phase1 📋 Clinical Research Protocol

Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Non-Hodgkin Lymphoma

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🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research

MRI Guided Management of Occlusive Peripheral Arterial Disease

Peripheral Vascular Diseases

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

CBD for Pain Following Orthopedic Shoulder Surgery

Shoulder Osteoarthritis

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury

Spinal Cord Injuries

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Bone Stimulator for Spondylolysis

Spondylolysis

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Ex Vivo T-Cell Depletion of Mobilized Peripheral Blood Stem Cells Via CD34-Selection

Stem Cell Transplant

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🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol

Personalized Transcranial Direct Current Stimulation in Stroke Recovery

Stroke

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🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol

VR-Based Cognitive Stimulation Games for Delirium Prevention

Surgery

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🟢 Recruiting Phase1 📋 Clinical Research Protocol

Autologous T-Cells Expressing a Second Generation CAR for Treatment of T-Cell Malignancies Expressing CD5 Antigen

T-cell Acute Lymphoblastic Lymphoma

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🟢 Recruiting Phase1 📋 Clinical Research Protocol

Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells

T-cell Acute Lymphoblastic Lymphoma

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)

Total Knee Arthroplasty

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🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic

Dexamethasone for Ureteral STent Symptoms (DUSTS)

Ureteral Stent-Related Symptom

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

Thymalfasin (Thymosin Alpha 1; Ta1) as an Enhancer of Vaccine Response Among Older Adults Receiving Booster Doses of COVID-19 Vaccine

Vaccine Response

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🟢 Recruiting Phase2 💊 Investigational Drug / Biologic

Venous Ethanol for Ventricular Tachycardia

Ventricular Tachycardia

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🟢 Recruiting Phase1 💊 Investigational Drug / Biologic

TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.

Viral Infection

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