100 Recruiting Studies at Sunnybrook Health Sciences Centre
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Toronto, Ontario
All research centersRecruiting Studies at Sunnybrook Health Sciences Centre
🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Characterizing MyMood Patterns of Use
Bipolar Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound
Brain Tumor
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
The TEACH (Texting After ACS Discharge) Pilot Randomized Trial
Coronary Artery Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
Dexmedetomidine to Reduce the Incidence of POCD After Open Cardiac Surgery
Delirium
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
The Sunnybrook Dementia Study
Dementia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
The Impact of Social Worker Referrals on Diabetes and Loneliness
Diabete Mellitus
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-3 (UNITED-3)
Glioblastoma Multiforme, Adult
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors
Glioma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Dose-Escalated MR-Guided Radiotherapy for Localized Prostate Cancer
Intermediate Risk Prostate Cancer (Diagnosis)
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)
Knee Osteoarthritis (Knee OA)
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders
Movement Disorders
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 ⚙️ Medical Device Protocol
Priming CBT With rTMS for OCD
Obsessive Compulsive Disorder (OCD)
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Oropharyngeal Exercises to Treat Obstructive Sleep Apnea
Obstructive Sleep Apnea
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Screening Using Portable Electronic Recorders for Sleep Apnea in Hypertensive At-Risk Populations (SUPER-SHARP Trial)
Obstructive Sleep Apnea
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
ExAblate Transcranial MRgFUS for Unilateral Pallidotomy for the Treatment of Parkinson's Disease
Parkinson's Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Effect of a Pre-operative Internet-based Educational Video on Post Operative Opioid Consumption
Patient Empowerment
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2)
Postoperative Cognitive Dysfunction
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
MRI Assisted Focal Boost With HDR Monotherapy for Prostate Cancer Patients
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Post-Prostatectomy Linac-Based Ultrahypofractionated Radiotherapy for Patients With Localized Prostate Cancer
SBRT
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Incidence of Adductor Canal Catheter Dislodgment
Total Knee Arthroplasty
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Three-Dimensional Ultrasound and Spectroscopy as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment
Breast Cancer
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Three-Dimensional Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
Breast Cancer
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Optimizing Ventilation to Improve Survival From Out-of-hospital Cardiac Arrest: the OPTIVO Randomized Controlled Trial
Cardiac Arrest
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase3 💊 Investigational Drug / Biologic
Sustained Mood Improvement With Laughing Gas Exposure
Major Depressive Disorder
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Ketogenic Diet and Neuromodulation in Treatment Resistant Depression
Major Depressive Disorder (MDD)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
CPAP Randomized Controlled Trial
Obstructive Sleep Apnea (OSA)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase3 💊 Investigational Drug / Biologic
Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)
Post Traumatic Headache
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
CEST for Prostate Biopsy
Prostate Cancer Detection
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic
A Dose Optimization Study of Enzalutamide in Elderly Patients With Advanced Prostate Cancer
Prostate Cancer Patients
View Study & Checklist ➔ 🟡 Not Yet Recruiting Interventional Protocol 📊 Observational Clinical Research
Baseline Knowledge of Stress Urinary Incontinence Among Urogynecology Patients
Stress Urinary Incontinence (SUI)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures
Traumatic Rib Fracture(s)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
rTMS for Apathy Clinical Trial
Alzheimer Disease
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2
Amyotrophic Lateral Sclerosis
View Study & Checklist ➔ 🟢 Recruiting Phase1 ⚙️ Medical Device Protocol
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive Disorder
Anorexia Nervosa (DSM-IV Revised Criteria)
View Study & Checklist ➔ 🟢 Recruiting Phase2 📋 Clinical Research Protocol
Combined Gamma Knife/Linac Radiosurgery for Large Brain Tumors / Metastases
Brain (Nervous System) Cancers
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS)
Brain Metastases
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Use of Quantitative Ultrasound to Guide Adaptive Chemotherapy Among Women With Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Investigation of Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Novel Magnetic Resonance Imaging-Guided Ultrasound-Stimulated Microbubble Radiation Treatment for Patients With Chest-Wall and Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
MRI-Guided Ultrasound Stimulated Microbubbles Radiation Treatment for Patients with Chest-Wall and Locally Advanced Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Ultrasound Imaging, Spectroscopy and Ultrasound Imaging of Vascular Blood Flow as Early Indicators of Breast Cancer Response to Neoadjuvant Treatment.
Breast Cancer Invasive
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Comparing Dual Mini-fragment Plating to Single Precontoured Plating of Acute Midshaft Clavicle Fractures Trial
Clavicle Fracture
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Hepatic Arterial Infusion Chemotherapy in Patients With Inoperable Colorectal Cancer Liver Metastasis
Colorectal Adenocarcinoma Metastatic in the Liver
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Redesigning the Surgical Pathway (PROMoTE)
Delirium
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
A Randomized Neuroimaging Trial of Psilocybin in Depression
Depressive Disorder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Assessment of Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Disorders of Consciousness
Disorders of Consciousness Due to Severe Brain Injury
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Comparing Virtual Reality Simulation to High Fidelity Simulation as an Educational Modality for Electroconvulsive Therapy Training: A Non-Inferiority Study
Education, Medical, Undergraduate
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
The HEROES Trial: Hyperbaric Oxygen Therapy for Endometriosis-Related Pain
Endometriosis-related Pain
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Analysis of Clinical Outcomes in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medication-Refractory Tremor
Essential Tremor
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy
GBM
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma
Glioblastoma
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer
Head and Neck Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Comparing Cardiac Chamber Measurements: TTE vs. TEE Under Anesthesia
Heart Chambers
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Levetiracetam for Persons at Risk for Alzheimer's Disease
Hippocampal Hyperactivation
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection
Hypertension
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Evaluation of Intercostal Neuralgia in Patients With Chest Tube Insertion After Traumatic Rib Fracture
Intercostal Nerve Injury
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)
Knee Osteoarthritis
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression
Late Life Depression (LLD)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
CEST in Low-grade Glioma Study
Low-grade Glioma
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications
Lymphoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
RCT of At-Home tDCS for Depression in Pregnancy
Major Depression
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
rTMS for Youth Inpatients With Depression
Major Depression Moderate
View Study & Checklist ➔ 🟢 Recruiting Phase1 ⚙️ Medical Device Protocol
qEEG Brain Signature of Depression & Neuromodulation-induced Recovery
Major Depressive Diorder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Interleaved TMS-fMRI in Ultra-treatment Resistant Depression
Major Depressive Disorder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
The Holographic Standardized Patient
Medical Emergencies
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
MRI-Guided Focused Ultrasound Radiosensitization for Patients With Malignant Melanoma and Non Melanoma Skin Cancer
Melanoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
I-CARE: A Pilot Study of Cognitive Behavioural Therapy(CBT) for Mood and Anxiety Disorders
Mood Disorders
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Life Following Excision of Neuroendocrine Tumors
Neuroendocrine (NE) Tumors
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Functional Outcomes and Control Using Synchron BCI - Canada
Neurologic Disorder
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
MRI Guided Closed-loop TMS-EEG
Normal Physiology
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing
Obstructive Sleep Apnea
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Treatment Refractory Obsessive Compulsive Disorder (OCD)
OCD
View Study & Checklist ➔ 🟢 Recruiting Phase3 💊 Investigational Drug / Biologic
Combination Therapy: Hyperbaric Oxygen and PENTOCLO for Treatment of Osteoradionecrosis of the Mandible
Osteoradionecrosis
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy
Ototoxic Hearing Loss
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery
Pancreas Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Intensive Care Unit Resident Scheduling Trial
Patient Safety
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery
Pneumothorax
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments
Post COVID-19 Condition
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Intravitreal Topotecan in the Repair of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy
Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Pilot Study of Dose Escalation in Prostate Radiotherapy Using the MR-Linac (DESTINATION-MRL)
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Improving Sexual Quality of Life - Randomized Trial of Two vs Five MRI Guided SABR Treatments for Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase2 / Phase3 📋 Clinical Research Protocol
2 Ablative RadioTherapy Treatments for Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Dose dE-eScalaTion IN prostATe radIOtherapy usiNg an MR-Linac in 2 Fractions
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Ultrasound Spectroscopy as Early Indicators of Radiation Treatment Response in Prostate, Rectum and Head & Neck Cancers
Prostate Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase1 ⚙️ Medical Device Protocol
Deep Brain Stimulation for Refractory PTSD
PTSD
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 💊 Investigational Drug / Biologic
Using Cannabis to Treat Restless Legs Syndrome
Restless Leg Syndrome (RLS)
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares
Rheumatoid Arthritis (RA)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture
Rib Fractures
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Sleep Apnea and Cognition in Older Adults
Sleep
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🩺 Clinical Procedure Protocol
Exploring the Feasibility of Cerebrospinal Fluid (CSF) and Blood Plasma Liquid Biopsy in Patients With Metastatic Solid Tumours and Primary Central Nervous System (CNS) Tumours: A Pilot Study
Solid Tumor Malignancies
View Study & Checklist ➔ 🟢 Recruiting Phase2 📋 Clinical Research Protocol
A Phase II Trial Evaluating Radiation Boost to Painful Spinal Metastases
Spine Metastasis
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Safety and Feasibility of Next-Generation Dome Helmet (NGDH) for Focused Ultrasound Neuromodulation in Substance Use Disorder (SUD)
Substance Use Disorder (SUD)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
Suicidal Ideation
View Study & Checklist ➔ 🟢 Recruiting Phase1 ⚙️ Medical Device Protocol
DBS for Cognitive Deficits After Traumatic Brain Injury
TBI Traumatic Brain Injury
View Study & Checklist ➔ 🟢 Recruiting Phase3 💊 Investigational Drug / Biologic
InTRavenous kEtAmine and immerSive virtUal Reality to Treat dEpression
Treatment Resistant Depression
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression
Treatment-Resistant Depression
View Study & Checklist ➔