32 Paid Clinical Research Studies in Iowa City, Iowa
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
Improving Antibiotic Use for ARIs in Urgent Care Clinics
Many clinicians prescribe antibiotics for patients with acute respiratory infections even when antibiotics will not benefit the patient because the infection is due to a virus. To
📍 University of Iowa Hospitals and Clinics — Iowa City, Iowa
View Study & Checklist ➔A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC
This clinical trial evaluates adding high-dose ascorbate (vitamin C) to a standard therapy for non-small cell lung cancer. The standard therapy is radiation therapy combined with c
📍 Holden Comprehensive Cancer Cener — Iowa City, Iowa
View Study & Checklist ➔Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial
The purpose of this single arm open label phase 1b clinical study is to see what effect zoledronic acid has on tumors in patients with resectable any grade chondrosarcoma prior to
📍 University of Iowa Hospitals and Clinics — Iowa City, Iowa
View Study & Checklist ➔RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
This a Phase 3, prospective, open-label, multicenter study of \[15-O\]-H2O injection for PET imaging of subjects with suspected CAD. Approximately 182 evaluable participants with s
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema
This study will use dual energy x-ray computed tomography (DECT) to evaluate the relationship between heterogeneous perfusion, hypoxia (low oxygen in inspired gas) and induction of
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Role of NADPH Oxidase in Microvascular Dysfunction Following GDM
The purpose of this investigation is to examine NADPH oxidase as a source of reactive oxygen species contributing to aberrant microvascular function in otherwise healthy women with
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma
This clinical trial evaluates adding ferumoxytol and pharamcologic ascorbate (vitamin C) to standard of care treatment of glioblastoma multiforme (a type of brain tumor) in adults.
📍 Department of Radiation Oncology at University of Iowa — Iowa City, Iowa
View Study & Checklist ➔A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme
This clinical trial evaluates adding high-dose ascorbate (vitamin C) to standard of care treatment of glioblastoma multiforme (a type of brain tumor) in adults. All subjects will r
📍 Holden Comprehensive Cancer Center — Iowa City, Iowa
View Study & Checklist ➔Target Engagement of Terazosin in Healthy Adults
The purpose of the study is to assess the target engagement of Terazosin (TZ) in a single cohort of 6 healthy adult participants. During the study participants will undergo PET/CT
📍 University of Iowa Hospitals and Clinics — Iowa City, Iowa
View Study & Checklist ➔Pharmacokinetics of Transdermal Metronidazole
This is a crossover pharmacokinetic clinical study in healthy volunteers to compare metronidazole delivery through skin when a gel or cream metronidazole product is applied to skin
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Safety and Efficacy Study in Subjects With Leber Congenital Amaurosis
The study is a Phase 3, open-label, randomized controlled trial of gene therapy intervention by subretinal administration of AAV2-hRPE65v2 (voretigene neparvovec-rzyl). At least tw
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Autoimmune Intervention Mastery Course Study
The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS), clinically i
📍 Univeristy of Iowa — Iowa City, Iowa
View Study & Checklist ➔Efficacy of Diet on Quality of Life in Multiple Sclerosis
The overarching goal of this project is to critically evaluate the efficacy of incorporating dietary guidance within multiple sclerosis (MS) care for improving long-term quality of
📍 Univeristy of Iowa — Iowa City, Iowa
View Study & Checklist ➔Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD
Non-alcoholic fatty liver disease (NAFLD) is a common complication of obesity which can progress to deadly complications like end-stage liver disease and hepatocellular carcinoma.
📍 University of Iowa Health Care — Iowa City, Iowa
View Study & Checklist ➔Cerebellar TDCS for SRPCS Treatment
This study is investigating the immediate and long-term effects of bilateral cerebellar transcranial direct current stimulation on cognition, balance, and symptom severity in peopl
📍 Thorsten of Rudroff — Iowa City, Iowa
View Study & Checklist ➔MR and Inflammation After Preeclampsia
The purpose of this investigation is to examine the role of inappropriate mineralocorticoid receptor activation in endothelial dysfunction and vascular inflammation in otherwise he
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Povidone Iodine for Caries Prevention
The goal of this clinical trial is to learn if Povidone Iodine works to prevent tooth decay and suppress the mouth germs responsible for tooth decay. The main questions it aims to
📍 University of Iowa College of Dentistry — Iowa City, Iowa
View Study & Checklist ➔Dimensional Changes: Randomized Clinical Trial
The goal of this clinical trial is to evaluate the dimensional changes in the short and long-term in patients with thin gum tissues who have gum grafts placed on either denuded bon
📍 University of Iowa College of Dentistry and Dental Clinics — Iowa City, Iowa
View Study & Checklist ➔A Stepped Care Approach to Treating Tobacco Use in Rural Veterans
Tobacco use remains prevalent among Veterans. Although effective smoking cessation interventions exist, long-term term quit rates remain sub-optimal. The project will investigate t
📍 Iowa City VA Healthcare System — Iowa City, Iowa
View Study & Checklist ➔Antibiotic Irrigations for Intra-Abdominal Drains
Intra-abdominal abscesses are pus-filled pouches in the abdominal cavity. Current standard of care includes drain placement in the abscess cavity to reach source control as well as
📍 The University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Ischemic Conditioning During Air tRansport Save penUmbral Tissue
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Sitagliptin With Pembro in RCC and Melanoma
This study is testing whether adding the drug sitagliptin to the standard immunotherapy pembrolizumab is safe and may help people with advanced melanoma or advanced renal cell carc
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction. Gre
📍 Integrative Laboratory of Applied Physiology and Lifestyle Medicine — Iowa City, Iowa
View Study & Checklist ➔ACEs, SIRT1, and Premature Vascular Aging in Humans
Adverse childhood experiences (ACEs) are directly related to cardiovascular morbidity and mortality, and impaired vascular endothelial function (VEF) is an independent predictor of
📍 Integrative Laboratory of Applied Physiology and Lifestyle Medicine — Iowa City, Iowa
View Study & Checklist ➔The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies
The overall purpose of this study is to understand the role of disrupted sleep in the association of exposure to early life adversity (adverse childhood experiences (ACEs)) with va
📍 Integrative Laboratory of Applied Physiology and Lifestyle Medicine — Iowa City, Iowa
View Study & Checklist ➔Aquagenic Wrinkling Prediction
The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Stimulant Effects on Disruptive Behavior
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will
📍 University of Iowa Hospitals and Clinics — Iowa City, Iowa
View Study & Checklist ➔Perinatal Autism Genetics and Epigenetics Study
The University of Iowa's Center for Disabilities and Development is researching how pregnancy, early childhood experiences, and genetic factors influence child development, with a
📍 Center fro Disabilities and Development — Iowa City, Iowa
View Study & Checklist ➔Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC
The goal of this clinical trial is to learn whether a combination of two chemotherapy drugs, Gemcitabine and Docetaxel, can treat high-grade non-muscle-invasive bladder cancer (HG-
📍 University of Iowa — Iowa City, Iowa
View Study & Checklist ➔Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer
This is a phase II, single arm, Simon two-stage design, trial, enrolling patients with cisplatin ineligible MIBC and/or those patients who decline cisplatin based NAC. Assess rate
📍 Holden Comprehensive Cancer Center - The University of Iowa — Iowa City, Iowa
View Study & Checklist ➔E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for the
📍 College of Nursing — Iowa City, Iowa
View Study & Checklist ➔Chronic Lung Allograft Dysfunction MRI Study
This studies purpose is to confirm the efficacy and efficiency of using OE-MRI and MRI with hyperpolarized gas techniques and Iodinated contrast CT scan, this will enhance understa
📍 University of Iowa — Iowa City, Iowa
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