Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema (NCT02682147)
🩺 Plain-English Summary (8th-Grade Level)
This study will use dual energy x-ray computed tomography (DECT) to evaluate the relationship between heterogeneous perfusion, hypoxia (low oxygen in inspired gas) and induction of pulmonary vascular dilatation to characterize emphysema susceptibility in a normal smoking population. The investigators will correlate DECT measures of perfusion with lung injury measured by single photon emission computed tomography (SPECT). The investigators will study the effect of pulmonary arterial vasodilation to see if it eliminates indices of persistent lung injury in smokers that are susceptible to emphysema
Who can join: Review the eligibility criteria below.
Location: University of Iowa — Iowa City, Iowa
Age range: 25 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Iowa — Iowa City, Iowa
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Emphysema
- Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial) — Birmingham, Alabama
- Zephyr Valve Registry (ZEVR) — Birmingham, Alabama
- Emphysema Research Registry and Biosample Repository — Pittsburgh, Pennsylvania
- Characterizing Matrix Metalloproteinase-12 (MMP12) in Sputum — Hamilton, Ontario
- STRIVE Post-Market Registry Study — Phoenix, Arizona
Explore by condition: All Emphysema clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.