34 Paid Clinical Research Studies in Bethesda, Maryland
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
Screening for Alpha Thalassemia in Healthy Volunteers
Background: Alpha thalassemia is a blood disorder. It is caused by genetic deletions. Part of the DNA is missing from a group of genes called alpha globin. Alpha thalassemias are
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
Magnetic Resonance Imaging (MRI) unlike X-rays and CT-scans does not use radiation to create a picture. MRI use as the name implies, magnetism to create pictures with excellent ana
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Radium-223 in Biochemically Recurrent Prostate Cancer
Background: Some men who have been treated for localized prostate cancer with surgery or radiation still show signs of the disease in their blood. This is called biochemically rec
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Evaluation of the Genetics of Bipolar Disorder
This study looks to identify genes that may affect a person's chances of developing bipolar disorder (BP) and related conditions.
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation
Background: Bronchiolitis obliterans syndrome (BOS) is a complication people can experience after hematopoietic stem cell transplant. It usually affects people with chronic graft
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide
Background: CGD causes infections and inflammation. The only cure currently is a bone marrow transplant. Most often a perfectly matched bone marrow donor is used. Researchers want
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)
Background: Chronic granulomatous disease (CGD) is a rare immune disorder that can cause serious infections throughout the body. The only cure for CGD is a stem cell transplant. T
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies
Background: About 23,000 people die from B-cell cancers in the US each year. These cancers, often called leukemia or lymphoma, affect a type of white blood cell called B cells. Th
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Chronic Pain Management In Primary Care Using Behavioral Health Consultants
The purpose of this randomized pragmatic trial is to assess the effect of monthly booster contacts on long-term Brief Cognitive Behavioral Therapy for Chronic Pain (BCBT-CP) pain o
📍 Uniformed Services University for the Health Sciences — Bethesda, Maryland
View Study & Checklist ➔Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) Study
CIRV2 is a Phase IV randomized, open-label, trial of FDA-approved COVID-19 and/or influenza vaccines (no more than minimal risk) with longitudinal follow-up. In 2025 CIRV2 will com
📍 Walter Reed National Military Medical Center — Bethesda, Maryland
View Study & Checklist ➔Vaccine Responses to SARS-CoV-2 and Other Emerging Infectious Diseases
Background: Vaccines against SARS-CoV-2, the virus that causes COVID-19, have been highly effective against preventing severe disease. But the protective effects of these vaccines
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
A Phase 1b/2a, first-in-disease, open-label, multiple-ascending dose exploratory study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamic biomarker respon
📍 National Institutes of Health (NIH) - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) — Bethesda, Maryland
View Study & Checklist ➔Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
Background: -DOCK8 deficiency is a genetic disorder that affects the immune system and can lead to severe recurrent infections and possible death from infections or certain types
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Patient-Centered Assessment of Symptoms and Outcomes
Background: The cause of fatigue is not well understood. It can be felt differently by different people. Some people think there are different types of fatigue, with different cau
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency
Background: People with GATA-binding factor 2 (GATA2) deficiency have a mutation on the GATA2 gene. This gene affects immune function. People with this disease are prone to seriou
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Optimizing PTCy Dose and Timing
Background: Stem cell or bone marrow transplants can cure or control blood cancers. Sometimes the donor cells see the recipient's body as foreign. This can cause complications. A
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Honeycomb: Evaluation of Radiprodil in Children with GRIN-related Disorder
Study RAD-GRIN-101 is a phase 1B trial to assess safety, tolerability, PK, and potential efficacy of radiprodil for the treatment of GRIN-related disorder in children with a Gain-o
📍 Mid-Atlantic Epilepsy and Sleep Center — Bethesda, Maryland
View Study & Checklist ➔Moxetumomab Pasudotox-tdfk (Lumoxiti(TM)) and Either Rituximab (Rituxan(R)) or Ruxience for Relapsed Hairy Cell Leukemia
Background: Hairy cell leukemia (HCL) is a rare, slow-growing blood cancer in which the bone marrow makes too many of certain white blood cells. The antibody Rituximab/Ruxience bi
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Randomized Phase II Trial of Rituximab With Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia
Background: * Researchers are attempting to develop new treatments for hairy cell leukemia (HCL) that has not responded well to or has recurred after standard HCL therapies. One n
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔ASP-1929 Photoimmunotherapy (PIT) Study in Patients With Recurrent Head/Neck Cancer
A Phase 2, Open-label, Single-arm, Window of opportunity Study of ASP-1929 Photoimmunotherapy with Fluorescence Imaging in Patients with Operable Primary or Recurrent Head and Neck
📍 Center for Cancer Research — Bethesda, Maryland
View Study & Checklist ➔ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study
This study will examine genome sequencing in clinical research. Genome sequencing is a process in which researchers analyze (or sequence) part or all of the genome from a single pe
📍 Suburban Hospital — Bethesda, Maryland
View Study & Checklist ➔A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy
Background: Antiretroviral therapy (ART) can suppress HIV to undetectable levels in people, but the virus rebounds quickly if the drug treatment is stopped; this is because HIV ca
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
Background: Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. It causes lesions. These are usually on the skin but sometimes in the lymph nodes, lungs, and gastr
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
Background: Gene transfer is a new cancer therapy takes white blood cells from a person and grows them in a lab. The cells are changed with a virus to attack tumor cells, then ret
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Background: Blood stem cells in the bone marrow make all the cells to normally defend a body against disease. Allogeneic blood or marrow transplant is when these stem cells are tr
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)
Background: People with TRD are often helped by electroconvulsive therapy (ECT). But ECT can affect memory and thinking. Researchers want to study a treatment called TEST that use
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
Background: Many cancer cells produce substances called antigens that are unique to each cancer. These antigens stimulate the body s immune responses. One approach to treating the
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma
Background: Multiple myeloma (MM) is a tumor in which malignant plasma cells accumulate in the bone marrow. It can cause organ damage and is not curable. Researchers want to see i
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Background: \- Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. However, the genetic causes of
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Background: Neurofibromatosis type 1 (NF1) is a disorder that can cause plexiform neurofibromas (PNs). These are tumors that grow along nerves. Some PNs cause serious health probl
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer
Background: Cancers in and around the mouth associated with human papilloma virus (HPV) are common. Two treatments (the drug pembrolizumab and the HPV vaccine PRGN-2009) have been
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Understanding the Psychosocial Needs of Parents Who Have Lost a Child to Cancer
The purpose of this study is to understand the experiences and needs of parents who have lost a child to cancer. This will aid us in developing an intervention that may help parent
📍 NCI Clinical Center — Bethesda, Maryland
View Study & Checklist ➔Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma
Background: Lymphoma is a type of blood cancer. Blood cell transplant can cure some people with lymphoma. Researchers want to see if they can limit the complications transplant ca
📍 National Institutes of Health Clinical Center — Bethesda, Maryland
View Study & Checklist ➔A Study to Assess the Safety of SAB-176 to Prevent the Flu, Given IM in Healthy Adults Compared With Placebo
This study will evaluate the safety and tolerability of an intramuscular injection of SAB-176 intended for use as a pre/post prophylactic for influenza. This is a Phase 1, randomi
📍 Naval Medical Research Command (NMRC) — Bethesda, Maryland
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