30 Paid Clinical Research Studies in Boston, Massachusetts
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
Arthroscopic Labral Repair Versus Physical Therapy for Tears of the Acetabular Labrum
Tears of the acetabular labrum appear to be common with the prevalence of asymptomatic tears in the general population approaching 66% and 70% based on cadaveric dissection and mag
📍 MGH, Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma
This study is being conducted to learn about the effects of SC-PEG, which is a new form of a chemotherapy drug called asparaginase. Asparaginase is used to treat ALL and lymphoblas
📍 Children's Hospital Boston — Boston, Massachusetts
View Study & Checklist ➔RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS
The purpose of this research study is to determine the safety of the combination of RAD001 and PKC412 as a cancer treatment, and to establish the highest dose of RAD001 that can be
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies
The purpose of this study is to examine if it is feasible to administer decitabine and filgrastim after allogenic hematopoietic stem cell transplant (HCT) in children and young adu
📍 Boston Children's Hospital — Boston, Massachusetts
View Study & Checklist ➔Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN
This clinical trial involves individuals who have been diagnosed with Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), or MDS/m
📍 Dana-Farber Cancer Institute — Boston, Massachusetts
View Study & Checklist ➔Preoperative vs Postoperative IMRT for Extremity/Truncal STS
This study is designed to determine if preoperative image guided radiation therapy (IGRT) delivered using intensity modulated radiation therapy (IMRT) followed by surgery results i
📍 Dana Farber Cancer Institute — Boston, Massachusetts
View Study & Checklist ➔Better Real-time Information on Documentation of Goals of Care for Engagement in Serious Illness Communication
The goal of this study is to test the accuracy of Large Language Model-generated serious illness communication (SIC) summaries, the feasibility of delivering the SIC summaries, and
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔AGEN1423 and Botensilimab w/ or w/o Chemo in PDAC
The goal of this research study is to asses the safety and efficacy of the combination of AGEN1423 and Botensilimab with or without chemotherapies, gemcitabine and nab-paclitaxel,
📍 Beth Israel Deaconess Medical Center — Boston, Massachusetts
View Study & Checklist ➔Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells
📍 Dana-Farber Cancer Institute /ID# 231209 — Boston, Massachusetts
View Study & Checklist ➔Prospective Phenotyping of Autonomous Aldosterone Secretion
This prospective cohort study will investigate the physiology and progression of autonomous aldosterone secretion.
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔The Effects of Dupilumab on Allergic Contact Dermatitis
The aim of this study is to investigate the effects of dupilumab on allergic contact dermatitis.
📍 Brigham and Women's Hospital, Department of Dermatology — Boston, Massachusetts
View Study & Checklist ➔T-regulatory Cells in ALS
This study is a randomized, placebo-controlled, phase 2a trial to study the biological activity, safety, and tolerability of regulatory T Lymphocytes (Tregs) taken and expanded out
📍 Massachusetts General Hospital Neurological Clinical Research Institute — Boston, Massachusetts
View Study & Checklist ➔Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia
The VITamin D and OmegaA-3 TriaL (VITAL; NCT01169259) is a randomized clinical trial in 20,000 U.S. men and women studying whether taking daily dietary supplements of vitamin D3 (2
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔Longitudinal At Home Smell Testing to Detect Infection by SARS-CoV-2
The purpose of this study is to learn more about how to better track smell recovery in people who have been infected with the SARS-CoV-2 virus (which causes COVID-19). Many people
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruci
📍 Boston Children's Hospital — Boston, Massachusetts
View Study & Checklist ➔Addressing Anxiety in 2-3-Year-Olds: A Pilot Intervention Study
The purpose of this study is to test the feasibility and efficacy of intervening with 2-year-old children with elevated temperamental Fear and/or Shyness or 3-year-old children wit
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Evaluation of PET/MR in Patients Selected for Ablation Therapy
This study is performed to assess if PET-MR imaging can improve treatment of patients with irregular heart rate and heart failure. Heart failure occurs when the heart muscle is too
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Lung-Resident Memory Th2 Cells in Asthma
Determining how memory T helper type 2 (Th2) initiate recall responses to aeroallergens has the potential to change the therapeutic approach to allergic asthma, the most common ast
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC
To determine the cognitive and neurophysiological dose-response relationships of anodal tDCS to the left DLPFC as a function of absolute current intensity, individualized E-field i
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors
This research study involves a combination of three drugs given together as a possible treatment for malignant rhabdoid tumor, atypical teratoid rhabdoid tumor, epithelioid sarcoma
📍 Boston Children's Hospital — Boston, Massachusetts
View Study & Checklist ➔Phenotypic and Genetic Factors in Autism Spectrum Disorders
The purpose of the study is to collect phenotypic (observable characteristics) and genetic information about individuals with Autism Spectrum Disorders (ASDs) and their families.
📍 Children's Hospital Boston — Boston, Massachusetts
View Study & Checklist ➔Fecal Microbiota Transplant for Autobrewery Syndrome
The goal of this clinical trial is to study fecal microbiota transplantation(FMT) by oral capsule in people already diagnosed with auto-brewery syndrome (ABS, also known as gut fer
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Venetoclax Plus Inotuzumab for B-ALL
This research study is evaluating the safety and efficacy of administering venetoclax and inotuzumab ozogamicin in combination in patients with acute lymphoblastic leukemia (ALL)
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔Identification of Genetic Causes of Bicuspid Aortic Valve Disease
BAVgenetics is a partnership between Investigators at Boston University, Brigham and Women's Hospital, and Massachusetts General Hospital dedicated to discovering the genetic cause
📍 Boston Medical Center — Boston, Massachusetts
View Study & Checklist ➔International Bicuspid Aortic Valve Consortium (BAVCon)
Bicuspid aortic valve (BAV) disease is the most frequent congenital cardiac malformation, occurring in 0.5-1.2% of the US population. In young adults, it is generally a benign abno
📍 Tufts Medical Center — Boston, Massachusetts
View Study & Checklist ➔Low-Intensity Focused Ultrasound of the Amygdala for Bipolar Disorder
The specific aim of this proposed study is to investigate the feasibility and therapeutic potential of transcranial focused ultrasound (tFUS) as a treatment for bipolar disorder (B
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
The purpose of this study is to assess whether 480 mg/day magnesium glycinate supplementation for 12 weeks lowers blood pressure.
📍 Brigham and Women's Hospital — Boston, Massachusetts
View Study & Checklist ➔Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness
Phase 1 of the STIMPACT trial is an open label,dose-escalation,safety study of intravenous (IV) methylphenidate (MPH) therapy in patients with disorders of consciousness (DoC) caus
📍 Massachusetts General Hospital — Boston, Massachusetts
View Study & Checklist ➔Olaparib + Sapacitabine in BRCA Mutant Breast Cancer
This research study is studying a combination of drugs as a possible treatment for breast cancer with a BRCA mutation. The interventions involved in this study are: * Sapacitabin
📍 Dana Farber Cancer Institute — Boston, Massachusetts
View Study & Checklist ➔Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, follo
📍 Dana-Farber Cancer Institute — Boston, Massachusetts
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