34 Paid Clinical Research Studies in Pittsburgh, Pennsylvania
Filtered for protocols that accept healthy volunteers or mention compensation. Always confirm stipend details and screening with the study coordinator.
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
The purpose of this study is to evaluate the effectiveness and safety of the combination of Pembrolizumab (KEYTRUDA®) and the investigational drug, Metformin.
📍 Univ of Pittsburgh Medical Center Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Behavioral Alcohol Responses (BAR) Study
This study aims to identify risk factors that prospectively predict alcohol problems in young adults.
📍 Carnegie Mellon University — Pittsburgh, Pennsylvania
View Study & Checklist ➔Auriculotherapy in the Treatment of Pre-Operative Anxiety
The goal of this clinical trial is to use the validated PROMIS Emotional Distress - Anxiety - Short Form 8a and PROMIS Emotional Distress-Depression-Short Form pre-and post-interve
📍 UPMC Shadyside Hospital — Pittsburgh, Pennsylvania
View Study & Checklist ➔Semantic Feature Analysis Treatment for Aphasia
This randomized controlled comparative effectiveness study examines manipulation of a key component of an established and efficacious treatment for naming impairments in aphasia, a
📍 VA Pittsburgh Healthcare System — Pittsburgh, Pennsylvania
View Study & Checklist ➔Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers
This is a Phase 2 study to evaluate the efficacy, using objective response rate, of a non-myeloablative lymphodepleting preparative regimen followed by infusion of autologous Tumor
📍 UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Early Intervention for Youth at High Risk for Bipolar Disorder
Investigators will conduct a confirmatory efficacy trial of Interpersonal and Social Rhythm Therapy (IPSRT) delivered via telehealth for offspring of bipolar parents (OBP; age 12-1
📍 Nicole Arnold — Pittsburgh, Pennsylvania
View Study & Checklist ➔Preoperative Irradiation for Stage I Breast Cancer
The novel use of preoperative RT will have broad implications for breast cancer patients, most of whom present with early-stage disease. In the era of reduced chemotherapy delivery
📍 UPMC Magee Womens Hospital - Radiation Oncology — Pittsburgh, Pennsylvania
View Study & Checklist ➔Novel Strategies for Reducing Heart Disease Risk Disparities
This Western Pennsylvania-based study will (1) improve cardiovascular risk stratification to identify high-risk populations, (2) identify differences in cardiovascular risk, (3) ev
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔The Pittsburgh Study Early Childhood
The Early Childhood Collaborative of The Pittsburgh Study is a community-partnered, county-wide implementation of programs for children and families from birth through formal schoo
📍 Primary Care Health Services — Pittsburgh, Pennsylvania
View Study & Checklist ➔Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
This is a Phase 2 study to evaluate the efficacy of a non-myeloablative lymphodepleting preparative regimen followed by infusion of autologous TIL and high-dose aldesleukin in pati
📍 UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma
This is a prospective, randomized, open-label, exploratory trial of temozolomide-based chemo-radiotherapy which compares two widely used established radiation schedules with either
📍 University of Pittsburgh Medical Center, Radiation Oncology — Pittsburgh, Pennsylvania
View Study & Checklist ➔Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study
This study will evaluate the safety and feasibility of treatment involving a single infusion of donor-derived regulatory dendritic cells (DCreg) in first time, living donor renal t
📍 University of Pittsburgh, Starzl Transplantation Institute — Pittsburgh, Pennsylvania
View Study & Checklist ➔Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
This study is designed to learn about early brain development in children with Krabbe disease, and to use diffusion tensor imaging as an early diagnostic tool to identify newborns
📍 UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Zimberelimab (AB122) With TIGIT Inhibitor Domvanalimab (AB154) in PD-1 Relapsed/Refractory Melanoma
The main goal of this study is to establish the proportion of patients with objective response to zimberelimab/domvanalimab in PD-1 R/R melanoma patients.
📍 UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Effectiveness of the On the Move Group Exercise Program to Improve Mobility in Community-dwelling Older Adults
The purpose of this study is to test the effectiveness of On the Move (OTM) in terms of improving mobility among 502 older adults in 44 senior community centers and to evaluate int
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Development of Adaptive Deep Brain Stimulation for OCD
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Development of Adaptive Deep Brain Stimulation for OCD (Phase 1a)
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activit
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Posterior vs. Anterior Tympanostomy Tube Placement
The goal of this randomized clinical trial is to compare the results of ear tube placement in two different parts of the ear drum. The ear drum can be divided into four parts (call
📍 UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Systemic Immune Checkpoint Blockade and Intraperitoneal Chemo-Immunotherapy in Recurrent Ovarian Cancer
This is a phase II single arm efficacy/safety trial that will evaluate the effectiveness of combining intensive locoregional intraperitoneal (IP) chemoimmunotherapy of cisplatin wi
📍 Magee-Womens Hospital of UPMC — Pittsburgh, Pennsylvania
View Study & Checklist ➔Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and
📍 University of PIttsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression
The primary goal of the present prospective cohort study is to evaluate the effect of varying incidences of BOP at implant sites across 15 months of maintenance visits on the proba
📍 University of Pittsburgh School of Dental Medicine — Pittsburgh, Pennsylvania
View Study & Checklist ➔Personalizing Perioperative Analgesia in Children
In the United States alone, each year approximately 5 million children undergo painful surgery, many of them experience serious side-effects with opioids and inadequate pain relief
📍 UPMC Children's Hospital — Pittsburgh, Pennsylvania
View Study & Checklist ➔Spinal Cord Stimulation for the Treatment of Motor Deficits in People With Spinal Muscular Atrophy - Upper Limb
Spinal cord stimulation (SCS) has shown remarkable efficacy in restoring motor function in people with spinal cord injury by recruiting afferent input to enhance the responsiveness
📍 University of Pittsburgh — Pittsburgh, Pennsylvania
View Study & Checklist ➔Neoadjuvant Study of PD-1 Inhibitor Pembrolizumab in PD-1 Naive Cutaneous Squamous Cell Carcinoma (cSCC)
This phase II single-arm two-stage neoadjuvant study of pembrolizumab in patients with PD-1 naïve high-risk resectable cutaneous squamous cell carcinoma (cSCC) will be conducted ov
📍 UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
This is a Phase 2 study in which the efficacy of a non-myeloablative lymphodepleting preparative regimen followed by infusion of autologous TIL and high-dose aldesleukin in patient
📍 UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE
To test the efficacy of a web-based stepped collaborative care intervention to reduce symptoms of depression, pain, and fatigue and improve health-related quality of life (HRQL) in
📍 University of Pittsburgh Medical Center Montefiore Liver Cancer Center — Pittsburgh, Pennsylvania
View Study & Checklist ➔Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation
This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain act
📍 Carnegie Mellon University — Pittsburgh, Pennsylvania
View Study & Checklist ➔Prediction and Prevention of Postoperative Mortality and Morbidity
This study will contribute to creating a prospective and automated preoperative risk assessment algorithm for predicting 30-day mortality, major adverse cardiac and cerebrovascular
📍 UPMC Montefiore Hospital — Pittsburgh, Pennsylvania
View Study & Checklist ➔FIH Lead-in Study of YASO GEL Followed by a Phase 1 Randomized, Double-blind Study to Assess Safety and Pharmacokinetics of YASO GEL
The goal of this clinical trial is to assess the safety and pharmacokinetics of YASO GEL in healthy adult participants. This is a first-in-human study designed to understand how th
📍 UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania
View Study & Checklist ➔Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia
The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia. The main question
📍 UPMC Pain Management — Pittsburgh, Pennsylvania
View Study & Checklist ➔mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System
This study is designed to test Project LYNX, a program designed to help young adults (ages 18-29) with recent criminal legal system involvement can find and get connected to substa
📍 University of Pittsburgh, School of Public Health — Pittsburgh, Pennsylvania
View Study & Checklist ➔Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder
This pilot study will evaluate the use of deep transcranial magnetic stimulation (Deep TMS) to help adults with opioid use disorder (OUD) who are receiving medications for opioid u
📍 UPMC Presbyterian — Pittsburgh, Pennsylvania
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