๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-22

Decitabine in Treating Patients With Myelofibrosis (NCT00095784)

A Phase II Study of Decitabine in Myelofibrosis

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase II trial studies the side effects and how well decitabine works in treating patients with myelofibrosis, a cancer of the blood system associated with fibrosis (scar tissue) in the bone marrow that is advanced and for which there is no standard therapy. Decitabine may block the actions of some proteins that are responsible for turning certain genes off in various cancers including myelofibrosis.

Who can join: Review the eligibility criteria below.

Location: University of Chicago Comprehensive Cancer Center โ€” Chicago, Illinois

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (14 Sites)

  • University of Chicago Comprehensive Cancer Center โ€” Chicago, Illinois
  • Decatur Memorial Hospital โ€” Decatur, Illinois
  • NorthShore University HealthSystem-Evanston Hospital โ€” Evanston, Illinois
  • Ingalls Memorial Hospital โ€” Harvey, Illinois
  • Loyola University Medical Center โ€” Maywood, Illinois
  • Illinois CancerCare-Peoria โ€” Peoria, Illinois
  • Central Illinois Hematology Oncology Center โ€” Springfield, Illinois
  • Southern Illinois University School of Medicine โ€” Springfield, Illinois
  • Fort Wayne Medical Oncology and Hematology Inc-Parkview โ€” Fort Wayne, Indiana
  • Northern Indiana Cancer Research Consortium โ€” South Bend, Indiana
  • University of Maryland/Greenebaum Cancer Center โ€” Baltimore, Maryland
  • Oncology Care Associates PLLC โ€” Saint Joseph, Michigan
  • Ohio State University Comprehensive Cancer Center โ€” Columbus, Ohio
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—