🏛️ Verified NIH Record • Updated 2026-08-18

CINC424A2X01B Rollover Protocol (NCT02386800)

Open Label, Multi-center, Phase IV Study of Ruxolitinib or Ruxolitinib and Panobinostat Combination, for Patients Who Have Completed Prior Global Novartis or Incyte Sponsored Studies

🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic Sponsor: Novartis Pharmaceuticals

🩺 Plain-English Summary (8th-Grade Level)

This is a long term safety study for patients that have been treated with either ruxolitinib or a combination of ruxolitinib with panobinostat, on a Novartis or Incyte sponsored study, who have been judged by the study Investigator to benefit from ongoing treatment.

Who can join: Review the eligibility criteria below.

Location: Novartis Investigative Site — Darlinghurst, New South Wales

Age range: 1 Month to 100 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (97 Sites)

Showing the first 25 of 97 sites.

  • Novartis Investigative Site — Darlinghurst, New South Wales
  • Novartis Investigative Site — Herston, Queensland
  • Novartis Investigative Site — Wooloongabba, Queensland
  • Novartis Investigative Site — Bedford Park, South Australia
  • Novartis Investigative Site — Box Hill, Victoria
  • Novartis Investigative Site — Clayton, Victoria
  • Novartis Investigative Site — Franston, Victoria
  • Novartis Investigative Site — Perth, Western Australia
  • Novartis Investigative Site — St Leonards,
  • Novartis Investigative Site — Leuven, Vlaams Brabant
  • Novartis Investigative Site — Antwerp,
  • Novartis Investigative Site — Bruges,
  • Novartis Investigative Site — Liège,
  • Novartis Investigative Site — Pleven,
  • Novartis Investigative Site — Plovdiv,
  • Novartis Investigative Site — Sofia,
  • Novartis Investigative Site — Toronto, Ontario
  • Novartis Investigative Site — Santiago, RM
  • Novartis Investigative Site — Viña del Mar, Valparaiso
  • Novartis Investigative Site — Santiago,
  • Novartis Investigative Site — Hangzhou, Zhejiang
  • Novartis Investigative Site — Beijing,
  • Novartis Investigative Site — Paris,
  • Novartis Investigative Site — Dresden, Saxony
  • Novartis Investigative Site — Jena, Thuringia

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗