🏛️ Verified NIH Record • Updated 2025-11-20
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee (NCT01542580)
🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research Sponsor: Zimmer Biomet
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate performance of the Vanguard 360 revision knee system utilizing offset on either the tibial component, femoral component, or both in terms of the restoration of mechanical alignment, clinical outcomes and survivorship.
Who can join: Review the eligibility criteria below.
Location: Illinois Bone and Joint — Morton Grove, Illinois
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (12 Sites)
- Illinois Bone and Joint — Morton Grove, Illinois
- Orthopedic Institute of Henderson — Henderson, Nevada
- University of Utah Orthopedic Center — Salt Lake City, Utah
- OrthoVirginia West End Orthopedic Clinic — Richmond, Virginia
- University Hopital Pellenberg — Pellenberg,
- Aarhus university hospital — Aarhus,
- Ch Lyon Sud — Lyon,
- Klinik fur Endoprothetik und gelenkchirurgie — Bad Wildbad,
- IRCCS Istituto Ortopedico Galeazzi — Milan,
- Azienda Ospedaliero Universitaria Pisana — Pisa,
- University Hospital Mutua de Terrasa — Terrassa,
- Royal Orthopaedic Hospital — Birmingham,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.