BAsel Syncope EvaLuation (BASEL IX) Study (NCT01548352)
🩺 Plain-English Summary (8th-Grade Level)
Syncope is a major health problem. In the emergency department (ED), the management of patients with syncope still remains a clinical challenge because underlying diseases and prognosis can be extremely various. Structural heart disease and primary electrical disorders are major risk factors for sudden cardiac death and mortality in patients with syncope. In contrast, patients with reflex syncope and exclusion of structural heart disease have an excellent prognosis. Therefore The investigators test the hypothesis that the use of a meticulous patient history, clinical examination and novel biomarkers can improve the rapid and accurate diagnosis of cardiac syncope in patients presenting to the ED and is able to improve risk stratification regarding adverse outcomes. The prospective multicenter cohort study is designed to enroll 720 patients presenting with transient loss of consciousness within the last 12 hours to the ED. Blood samples for the measurement of novel biomarkers will be obtained at presentation. All patients will be contacted by phone at 6, 12 and 24 months to determine major adverse events (death, resuscitation, recurrence of syncope, hospitalization for syncope).
Who can join: Review the eligibility criteria below.
Location: Baylor College of Medicine — Houston, Texas
Age range: 40 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (15 Sites)
- Baylor College of Medicine — Houston, Texas
- Instituto Cardiovascular de Buenos Aires — Buenos Aires,
- Royal Brisbane and Women's hospital — Brisbane,
- Klinikum Nürnberg — Nuremberg, Bavaria
- Sant'Andrea Hospital — Rome,
- Christchurch Hospital — Christchurch,
- Medical University of Silesia — Zabrze,
- Hospital del Mar — Barcelona,
- Hospital Clinic of Barcelona — Barcelona,
- Hospital Universitario Clínico San Carlos — Madrid,
- Kantonsspital Baselland — Liestal, Basel-Landschaft
- Spital Lachen — Lachen, Canton of Schwyz
- University Hospital Basel — Basel,
- Luzern Kantonsspital — Lucerne,
- University Hospital Zurich — Zurich,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Syncope
- CSRS Implementation - A Pilot Study — Ottawa, Ontario
- Canadian Prehospital Syncope Risk Score (Prehospital CSRS) — Ottawa, Ontario
- Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial — Calgary, Alberta
- SW-RCT Implementation of Canadian Syncope Risk Score Based Practice Recommendations — Calgary, Alberta
- REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge -RCT — Ottawa, Ontario
Explore by condition: All Syncope clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.