SW-RCT Implementation of Canadian Syncope Risk Score Based Practice Recommendations (NCT04972071)
Multi-Centre Cluster-Randomized Implementation of Canadian Syncope Risk Score Based Practice Recommendations for Emergency Department Syncope Management
🩺 Plain-English Summary (8th-Grade Level)
Syncope is a common reason for emergency department (ED) presentation. While often benign, some patients have serious and life-threatening underlying causes, both cardiac and non-cardiac, which may or may not be apparent at the time of the initial ED assessment. Identifying which patients will benefit from further investigation, ongoing monitoring and/or hospital admission is essential to reduce both adverse outcomes and high costs. The research team has spent over a decade developing the evidence base for a risk stratification tool directed at optimizing the accuracy of ED decisions: the Canadian Syncope Risk Score (CSRS). This tool is now ready for the final phase of its introduction into clinical practice, namely a robust, multicentre implementation trial of the CSRS-based practice recommendations to demonstrate its real-world effectiveness. These recommendations, if applied, could lead to reduction in hospitalization with only 6% of high-risk patients requiring hospitalization, shorter ED lengths of stay for the 76% of ED syncope patients who are at low risk for 30-day serious outcomes, and more standardized disposition decisions, specifically discharge of 18% of medium-risk patients after appropriate discussion. Hence, the investigators hypothesize that an important reduction in hospitalization and ED disposition time can be achieved by implementing the CSRS-based recommendations with potential improvements in patient safety. The overall objective of this study is to evaluate the effectiveness of the knowledge translation (KT) of the CSRS-based practice recommendations in multiple Canadian EDs using a stepped wedge cluster randomized trial (SW-CRT) on health care efficiency and patient safety.
Who can join: Review the eligibility criteria below.
Location: Foothills Medical Centre — Calgary, Alberta
Age range: 18 Years
🧪 Interventions in This Study
- Knowledge translation (KT) of the CSRS based practice recommendations (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (15 Sites)
- Foothills Medical Centre — Calgary, Alberta
- St. Boniface Hospital — Winnipeg, Manitoba
- Health Sicence North — Greater Sudbury, Ontario
- Hawkesbury and District General Hospital — Hawkesbury, Ontario
- London Health Sciences Centre — London, Ontario
- North Bay Regional Health Centre — North Bay, Ontario
- Thunder Bay Regional Health Sicences Centre — Thunder Bay, Ontario
- University Health Network — Toronto, Ontario
- Niagara Health — Welland, Ontario
- Winchester District Memorial Hospital — Winchester, Ontario
- Jewish General Hospital — Montreal, Quebec
- Royal Victoria Hospital & Montreal General Hospital — Montreal, Quebec
- Centre hospitalier de l'Université Laval — Québec, Quebec
- Hotel Dieu Hospital of Lévis — Québec, Quebec
- Hôpital de L'Enfant-Jésus — Québec, Quebec
📞 Contact the Study Coordinator
Phone: (403) 944-1110
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Syncope
- CSRS Implementation - A Pilot Study — Ottawa, Ontario
- BAsel Syncope EvaLuation (BASEL IX) Study — Houston, Texas
- Canadian Prehospital Syncope Risk Score (Prehospital CSRS) — Ottawa, Ontario
- Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial — Calgary, Alberta
- REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge -RCT — Ottawa, Ontario
Explore by condition: All Syncope clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.