Sympathetic Overactivity in Post-traumatic Stress Disorder (NCT01627301)
Mechanisms of Sympathetic Overactivity in Post-traumatic Stress Disorder
🩺 Plain-English Summary (8th-Grade Level)
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily DGB therapy or transcutaneous vagus nerve stimulation (tVNS) therapy improves SNS activity at rest and during stress.
Who can join: Review the eligibility criteria below.
Location: Atlanta VA Medical Center — Decatur, Georgia
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Atlanta VA Medical Center — Decatur, Georgia
📞 Contact the Study Coordinator
Phone: (404) 321-6111
Email: deirdre.dixon@emory.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Post-traumatic Stress Disorder
- An Intervention to Enhance Well-Being in Trauma Exposed New Mothers — Detroit, Michigan
- MDMA-assisted Massed Prolonged Exposure for PTSD — San Diego, California
- Stellate Ganglion Block for PTSD — Long Beach, California
- MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders — Boulder, Colorado
- Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study — Ganges, British Columbia
Explore by condition: All Post-traumatic Stress Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.