Stellate Ganglion Block for PTSD (NCT05169190)
Efficacy and Safety of Stellate Ganglion Block for Post-traumatic Stress Disorder in Veterans
🩺 Plain-English Summary (8th-Grade Level)
Posttraumatic Stress Disorder (PTSD) is a debilitating condition that affects about 15% of Veterans. Current treatments for Veterans with PTSD include medications and psychological therapies that help to process and desensitize to traumatic events. While effective for many, these treatments do not work for all patients, and many may refuse them. Stellate Ganglion Block (SGB), established to treat pain and other conditions, has shown promise for PTSD: early small studies show it may work fast and greatly reduce symptoms. However, data from larger studies are not clear about SGBs effects. A definitive trial is needed, especially for the Veteran population. This large, well-powered, randomized, sham-controlled trial of SGB for PTSD will assess the short-term efficacy of this intervention, the durability of the effects and the safety of the treatment. Additionally, this study will provide critically important information about biological effects of SGB and potential mechanisms of action. This timely study is critical to help VA clinicians better decide about the merits of SGB for PTSD.
Who can join: Review the eligibility criteria below.
Location: VA Long Beach Healthcare System, Long Beach, CA — Long Beach, California
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
- Stellate Ganglion Block (PROCEDURE)
- Sham Stellate Ganglion Block (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (6 Sites)
- VA Long Beach Healthcare System, Long Beach, CA — Long Beach, California
- James A. Haley Veterans' Hospital, Tampa, FL — Tampa, Florida
- Minneapolis VA Health Care System, Minneapolis, MN — Minneapolis, Minnesota
- VA Salt Lake City Health Care System, Salt Lake City, UT — Salt Lake City, Utah
- White River Junction VA Medical Center, White River Junction, VT — White River Junction, Vermont
- William S. Middleton Memorial Veterans Hospital, Madison, WI — Madison, Wisconsin
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Post-traumatic Stress Disorder
- An Intervention to Enhance Well-Being in Trauma Exposed New Mothers — Detroit, Michigan
- MDMA-assisted Massed Prolonged Exposure for PTSD — San Diego, California
- MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers and First Responders — Boulder, Colorado
- Intra-Sessional Autonomic Arc Detection in Ketamine-Assisted Therapy for PTSD: A Signal Characterisation Pilot Study — Ganges, British Columbia
- Sympathetic Overactivity in Post-traumatic Stress Disorder — Decatur, Georgia
Explore by condition: All Post-traumatic Stress Disorder clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.