Modafinil and Cognitive Function in POTS (NCT01988883)
Modafinil and Cognitive Function in Postural Tachycardia Syndrome
🩺 Plain-English Summary (8th-Grade Level)
A common complaint among patients with Postural Tachycardia Syndrome (POTS) is "brain fog" or difficulty concentrating. This problem is poorly understood. The purpose of this study is to better understand the cognitive dysfunction associated POTS, and to determine optimal treatment strategies for this condition. In this study, the investigators will test the hypothesis that acute administration of the psychostimulant drug modafinil can improve seated measures of cognitive function in patients with POTS.
Who can join: Review the eligibility criteria below.
Location: Vanderbilt University — Nashville, Tennessee
Age range: 18 Years to 60 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Vanderbilt University — Nashville, Tennessee
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Postural Tachycardia Syndrome
- Acute Salt Handling in Orthostatic Intolerance — Nashville, Tennessee
- Phenotyping Mitochondrial and Immune Dysfunction in POTS With Targeted Clinical Intervention. — La Jolla, California
- Sleep Actigraphy in Postural Tachycardia Syndrome (POTS) — Nashville, Tennessee
- Vagal Stimulation in POTS — Nashville, Tennessee
- fMRI in Postural Tachycardia Syndrome — Hershey, Pennsylvania
- Autonomic Determinants of POTS - Pilot 2 — Nashville, Tennessee
Explore by condition: All Postural Tachycardia Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.