Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD) (NCT02661451)

🧪 Interventions in This Study

• SAPIEN 3 THV (DEVICE)
• Optimal Heart Failure Therapy (BIOLOGICAL)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (51 Sites)

Showing the first 25 of 51 sites.

• Chandler Regional Medical Center — Chandler, Arizona
• UCSD/Sulpizio Cardiovascular Center — La Jolla, California
• University of Southern California - Los Angeles — Los Angeles, California
• UCLA Medical Center — Los Angeles, California
• St. Joseph Hospital — Orange, California
• UCSF — San Francisco, California
• Medical Center of the Rockies — Loveland, Colorado
• Yale University — New Haven, Connecticut
• Medstar Washington Hospital Center — Washington D.C., District of Columbia
• University of Miami — Miami, Florida
• Cleveland Clinic Florida — Weston, Florida
• Advocate Christ Hospital — Chicago, Illinois
• Northwestern University — Chicago, Illinois
• Alexian Brothers Medical Center — Elk Grove Village, Illinois
• Evanston Hospital/NorthShore Univ. Health System — Evanston, Illinois
• Advocate Lutheran General Hospital — Park Ridge, Illinois
• Carle Foundation Hospital — Urbana, Illinois
• Maine Medical Center — Portland, Maine
• Tufts Medical Center — Boston, Massachusetts
• Massachusetts General Hospital — Boston, Massachusetts
• Beaumont Hospital — Royal Oak, Michigan
• Ascension St. Mary's Hospital — Saginaw, Michigan
• Minneapolis Heart Institute — Minneapolis, Minnesota
• Mayo Clinic - Rochester — Rochester, Minnesota
• HealthEast Medical Research Institute — Saint Paul, Minnesota

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Aortic Valve Stenosis

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• Prolonged Continuous ECG Monitoring Prior to Transcatheter Aortic Valve Implantation — Québec, Quebec
• Inspiris Resilia Durability Registry — Sankt Pölten,
• Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients — Phoenix, Arizona
• Platelet Adhesion in the Pathobiology of Aortic Stenosis — Charlottesville, Virginia

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.