Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS) (NCT02664831)
Immunoinflammatory and Metabolic Responses in Post Cardiac Arrest Syndrome (PCAS)
🩺 Plain-English Summary (8th-Grade Level)
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after cardiac arrest. Investigators have shown that cardiac arrest induces changes in the numbers and properties of circulating immune cells, shifting the balance towards a pro-inflammatory phenotype and there is increased interest in the inflammatory pathways and the signaling mechanisms through which they are modulated. Participants will undergo blood sampling during 7 days following cardiac arrest, and analyses performed. Patient characteristics, clinical circumstances, and outcomes will be recorded and their associations with these inflammatory pathways characterized.
Who can join: Review the eligibility criteria below.
Location: Maine Medical Center — Portland, Maine
Age range: 18 Years
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Maine Medical Center — Portland, Maine
📞 Contact the Study Coordinator
Phone: (207) 662-2179
Email: david.seder@mainehealth.org
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiac Arrest
- RACE-CARS - RAndomized Cluster Evaluation of Cardiac ARrest Systems — Durham, North Carolina
- Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns — Edmonton,
- Optimizing Ventilation to Improve Survival From Out-of-hospital Cardiac Arrest: the OPTIVO Randomized Controlled Trial — Toronto, Ontario
- Targeted Temperature Management at 33°C Versus Controlled Normothermia for In-hospital Cardiac Arrest — Brussels,
- Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study — Los Angeles, California
- Early Amiodarone in Shockable Cardiac Arrest — Portland, Oregon
Explore by condition: All Cardiac Arrest clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.