A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH) (NCT02724228)
A Phase 2, Open-Label, Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of BMN 111 in Children With Achondroplasia
🩺 Plain-English Summary (8th-Grade Level)
This is a Phase 2, Open-Label, Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of BMN 111 in Children with Achondroplasia. The primary objective is to evaluate the long-term safety and tolerability of daily SC injections of BMN 111 in children with ACH who have completed two years of treatment in the 111-202 study.
Who can join: Review the eligibility criteria below.
Location: Children's Hospital & Research Center Oakland — Oakland, California
Age range: 7 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- Children's Hospital & Research Center Oakland — Oakland, California
- Harbor - UCLA Medical Center — Torrance, California
- Ann and Robert H. Lurie Childrens Hospital of Chicago — Chicago, Illinois
- Johns Hopkins McKusick - Institute of Genetic Medicine — Baltimore, Maryland
- Vanderbilt University — Nashville, Tennessee
- Baylor College of Medicine — Houston, Texas
- Murdoch Children's Research Institute — Parkville, Victoria
- Institut Necker — Paris,
- Guys & St. Thomas NHS Foundation Trust Evelina Hospital — London,
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Achondroplasia
- An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia — Oakland, California
- An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia — Oakland, California
- Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH) — Oakland, California
- A Study of TYRA-300 in Children With Achondroplasia: BEACH301 — Torrance, California
- VIrtual STudy in Achondroplasia for the US (VISTA) — Oakland, California
Explore by condition: All Achondroplasia clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.