A Study of TYRA-300 in Children With Achondroplasia: BEACH301 (NCT06842355)

🧪 Interventions in This Study

• TYRA-300 0.125 mg/kg (DRUG)
• TYRA-300 0.25 mg/kg (DRUG)
• TYRA-300 0.375 mg/kg (DRUG)
• TYRA-300 0.50 mg/kg (DRUG)
• TYRA-300 0.625 mg/kg (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (24 Sites)

• Lundquist Institute for Biomedical Innovation — Torrance, California
• Children's Hospital Colorado — Aurora, Colorado
• Nemours Alfred I duPont Hospital for Children — Wilmington, Delaware
• Johns Hopkins University School of Medicine — Baltimore, Maryland
• Uncommon Cures — Chevy Chase, Maryland
• University of Missouri — Columbia, Missouri
• Washington University — St Louis, Missouri
• Duke University Hospital — Durham, North Carolina
• Vanderbilt University Medical Center — Nashville, Tennessee
• Children's Medical Center, Dallas — Dallas, Texas
• University of Texas Health Science Center Medical School at Houston — Houston, Texas
• University of Wisconsin-Madison — Madison, Wisconsin
• The Children's Hospital at Westmead — Westmead, New South Wales
• Royal Children's Hospital — Parkville, Victoria
• Women's and Children's Health Research Institute, University of Alberta — Edmonton, Alberta
• Children's Hospital of Eastern Ontario — Ottawa, Ontario
• The Hospital for Sick Children — Toronto, Ontario
• Imagine Institute — Paris,
• UMC Utrecht — Utrecht,
• Unidad de Cirugía Artroscópica (MIKS Hospital) — Vitoria-Gasteiz, Alava
• Hospital Univeristario La Paz — Madrid, Madrid
• Astrid Lindgren Children's Hospital (Karolinska University Hospital) — Stockholm,
• Great Ormond Street Hospital — London, Greater London
• Sheffield Children's Hospital — Sheffield, South Yorkshire

📞 Contact the Study Coordinator

Phone: (619) 728-4805

Email: ACH@tyra.bio

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Achondroplasia

• A Study to Evaluate Long-Term Safety, Tolerability, & Efficacy of BMN 111 in Children With Achondroplasia (ACH) — Oakland, California
• An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia — Oakland, California
• An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia — Oakland, California
• Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH) — Oakland, California
• VIrtual STudy in Achondroplasia for the US (VISTA) — Oakland, California

Explore by condition: All Achondroplasia clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.