🏛️ Verified NIH Record • Updated 2026-04-02
Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair (NCT02803957)
Randomized Trial of the NeoChord™ DS1000™ System Versus Open Surgical Repair
🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: NeoChord
🩺 Plain-English Summary (8th-Grade Level)
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Who can join: Review the eligibility criteria below.
Location: Mercy General Hospital — Sacramento, California
Age range: 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (14 Sites)
- Mercy General Hospital — Sacramento, California
- Stanford University — Stanford, California
- MedStar Washington Hospital Center — Washington D.C., District of Columbia
- Piedmont Heart Institute — Atlanta, Georgia
- Franciscan Health — Indianapolis, Indiana
- Johns Hopkins University — Baltimore, Maryland
- University of Michigan — Ann Arbor, Michigan
- Mount Sinai, Icahn School of Medicine — New York, New York
- Columbia University Medical Center — New York, New York
- Pinnacle Health — Harrisburg, Pennsylvania
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- St. Thomas — Nashville, Tennessee
- Baylor - Plano — Plano, Texas
- Valley Health System | Virginia — Winchester, Virginia
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mitral Valve Insufficiency
- Long Term Follow Up for CTSN Mitral Valve Repair Studies — Los Angeles, California
- PARTNER 3 Trial - Mitral Valve in Valve — Atlanta, Georgia
- REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial — Ottawa, Ontario
- Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System — Phoenix, Arizona
- The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study — New York, New York
Explore by condition: All Mitral Valve Insufficiency clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.