🏛️ Verified NIH Record • Updated 2025-10-31
PARTNER 3 Trial - Mitral Valve in Valve (NCT03193801)
PARTNER 3 Trial - SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Mitral Bioprosthetic Valve
🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: Edwards Lifesciences
🩺 Plain-English Summary (8th-Grade Level)
To assess the safety and effectiveness of the SAPIEN 3 transcatheter heart valve in patients with a failing mitral bioprosthetic valve.
Who can join: Review the eligibility criteria below.
Location: Emory University — Atlanta, Georgia
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (12 Sites)
- Emory University — Atlanta, Georgia
- Northwestern University — Chicago, Illinois
- Northshore University Health System Research Institution — Evanston, Illinois
- Brigham and Women's Hospital — Boston, Massachusetts
- Mayo Clinic — Rochester, Minnesota
- Barnes-Jewish Hospital/ Washington University — St Louis, Missouri
- NYU Lagone Medical Center — New York, New York
- Providence Heart & Vascular Institution — Portland, Oregon
- The Heart Hospital of Baylor Plano — Plano, Texas
- The Prince Charles Hospital — Chermside, Queensland
- Instituto do Coração da Universidade de São Paulo — Cerqueira César, São Paulo
- Instituto Dante Pazzanese de Cardiologia — Vila Mariana, São Paulo
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Mitral Valve Insufficiency
- Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair — Sacramento, California
- Long Term Follow Up for CTSN Mitral Valve Repair Studies — Los Angeles, California
- REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial — Ottawa, Ontario
- Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System — Phoenix, Arizona
- The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study — New York, New York
Explore by condition: All Mitral Valve Insufficiency clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.