Trial on Radical Upfront Surgery in Advanced Ovarian Cancer (NCT02828618)
🩺 Plain-English Summary (8th-Grade Level)
This study consists of three parts, whereas Part 1 and Part 2 are performed in Germany only, and Part 3 is a multinational trial. All patients with suspicion of advanced ovarian cancer are detected in the participating study centers in a pre-screening. The study centers will register all patients with suspected ovarian cancer in a screening log. After the patients have given informed consent, they can be enrolled in different parts of the study. TRUST-Trial: This part compares two strategies in the therapy of advanced ovarian cancer. En detail, this part of the trial will evaluate if one of two strategies of timing surgery within the therapeutic procedures may show any significant advances in terms of overall survival over the other.
Who can join: Review the eligibility criteria below.
Location: Memorial Sloan Kettering Cancer Center — New York, New York
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (20 Sites)
- Memorial Sloan Kettering Cancer Center — New York, New York
- Medical University of Vienna — Vienna,
- University Hospital, Rigshospitalet — Copenhagen,
- Institut Bergonié — Bordeaux,
- Hôpital Européen Georges Pompidou (HEGP) — Paris,
- Institute Gustave Roussy — Villejuif,
- Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Klinik für Gynäkologie — Berlin,
- Universitätsklinikum Carl Gustav Carus Dresden, Klinik & Poliklinik f. Frauenheilkunde & Geburtshilfe — Dresden,
- Kaiserswerther Diakonie; Florence-Nightingale-Hospital — Düsseldorf,
- Kliniken Essen-Mitte, Evang. Huyssens-Stiftung, Klinik für Gynäkologie und gyn. Onkologie — Essen,
- Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Gynäkologie — Hamburg,
- Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Klinikum der Universität München — München,
- Klinikum rechts der Isar, Frauen- und Poliklinik — München,
- Universitätsklinikum Tübingen — Tübingen,
- European Institute of Oncology; Gynecologic Cancer Surgery — Milan,
- Fondazione IRCCS Istituto Nazionale Tumori - Milan — Milan,
- Istituto Nazionale per lo Studio e la Cura dei Tumori di Napoli — Naples,
- Skane University Hospital — Lund,
- Karolinska University Hospital — Solna,
- Imperial College London, Hammersmith Hospital, Surgery&Cancer — London,
📞 Contact the Study Coordinator
Phone: (800) 525-2225
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ovarian Cancer
- Prehabilitation Care for Women With Advanced Ovarian Cancer Receiving Neoadjuvant Chemotherapy — New York, New York
- Safety and Efficacy of Anti-CD47, ALX148 in Combination With Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer — Pittsburgh, Pennsylvania
- Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) — Duarte, California
- Tuvusertib Combined With Niraparib or Lartesertib in Participants With Epithelial Ovarian Cancer (DDRiver EOC 302) — Little Rock, Arkansas
- NeoVax With Nivolumab in Patients With Ovarian Cancer — Boston, Massachusetts
Explore by condition: All Ovarian Cancer clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.