🏛️ Verified NIH Record • Updated 2026-04-02

Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) (NCT03772028)

Phase III Randomized Clinical Trial for Stage III Epithelial Ovarian Cancer Randomizing Between Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy

🔵 Active, Not Recruiting Phase3 💊 Investigational Drug / Biologic Sponsor: The Netherlands Cancer Institute

🩺 Plain-English Summary (8th-Grade Level)

stage III epithelial ovarian cancer randomizing between primary cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy

Who can join: Review the eligibility criteria below.

Location: City of Hope — Duarte, California

Age range: 18 Years

🧪 Interventions in This Study

📋 "Do I Qualify?" — 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (28 Sites)

Showing the first 25 of 28 sites.

  • City of Hope — Duarte, California
  • MSKCC New York — New York, New York
  • Rigshospitalet Copenhagen — Copenhagen,
  • CHU de Besancon — Besançon,
  • Institut Bergonié — Bordeaux,
  • o Institut Bergonié, Bordeaux — Bordeaux,
  • CHU Lille — Lille,
  • Centre Leon Berard, Lyon — Lyon,
  • CHU Lyon — Lyon,
  • Institut du Cancer Montpellier — Montpellier,
  • Institut de Cancerologie de l'Ouest, ICO Nantes) — Nantes,
  • Institut Curie Paris — Paris,
  • CHRU Strasbourg — Strasbourg,
  • Oncopole, Institute Universitaire du Cancer de Toulouse (IUCT Toulouse) — Toulouse,
  • Mater Misericordiae University Hospital, Dublin — Dublin,
  • Policlinico Sant'Orsola, Bologna — Bologna,
  • Fondazione Policlinico A Gemelli IRCCS — Roma,
  • Antoni van leeuwenhoek — Amsterdam, North Holland
  • Amsterdam UMC — Amsterdam,
  • Catharina Hospital — Eindhoven,
  • Medisch Spectrum Twente — Enschede,
  • UMCG — Groningen,
  • Leiden University Medical Center (LUMC) — Leiden,
  • Maastricht UMC+ — Maastricht,
  • Radboud MC — Nijmegen,

📞 Contact the Study Coordinator

Phone: (800) 826-4673

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Ovarian Cancer clinical trials

💡 How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
🏛️ View Official NIH Record ↗