🏛️ Verified NIH Record • Updated 2025-07-08
Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients (NCT02922036)
Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in Non-Responders, Previously Untreatable and High Risk Upgrade Patients (SOLVE CRT)
🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol Sponsor: EBR Systems, Inc.
🩺 Plain-English Summary (8th-Grade Level)
This study is a prospective, multi-center, pivotal trial to study the safety and efficacy of the WiSE-CRT System for Cardiac Re-synchronization Therapy.
Who can join: Review the eligibility criteria below.
Location: Heart Center Research — Huntsville, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (68 Sites)
Showing the first 25 of 68 sites.
- Heart Center Research — Huntsville, Alabama
- University of California, San Diego — La Jolla, California
- Broward Health Medical Center — Fort Lauderdale, Florida
- St. Vincent's Healthcare — Jacksonville, Florida
- Watson Clinic — Lakeland, Florida
- Naples Community Hospital — Naples, Florida
- Northside Hospital and Heart Institute — St. Petersburg, Florida
- Piedmont Heart Institute — Atlanta, Georgia
- Emory Healthcare — Atlanta, Georgia
- Prairie Heart — Springfield, Illinois
- St. Vincent's Hospital and Healthcare Center — Indianapolis, Indiana
- University of Iowa — Iowa City, Iowa
- Saint Luke's Health System Kansas City — Kansas City, Kansas
- The University of Kansas Medical Center — Kansas City, Kansas
- Baptist Health Lexington — Lexington, Kentucky
- Ochsner Medical Center - Baton Rouge — Baton Rouge, Louisiana
- University of Michigan — Ann Arbor, Michigan
- Michigan Heart — Canton, Michigan
- Henry Ford Hospital — Detroit, Michigan
- William Beaumont Hospital — Hazel Park, Michigan
- Sparrow Hospital — Lansing, Michigan
- Minneapolis Heart Institute — Minneapolis, Minnesota
- Mayo Clinic — Rochester, Minnesota
- United Heart and Vascular Clinic — Saint Paul, Minnesota
- Methodist Physicians Clinic Heart Consultants — Omaha, Nebraska
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.