๐๏ธ Verified NIH Record โข Updated 2026-06-27
Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis (NCT02968810)
Statin Therapy to Reduce Disease Progression From Liver Cirrhosis to Cancer
๐ต Active, Not Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)
๐ฉบ Plain-English Summary (8th-Grade Level)
This phase II trial studies how well simvastatin works in preventing liver cancer in patients with liver cirrhosis. Simvastatin may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Who can join: Review the eligibility criteria below.
Location: Cedars-Sinai Medical Center โ Los Angeles, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (5 Sites)
- Cedars-Sinai Medical Center โ Los Angeles, California
- MedStar Georgetown University Hospital โ Washington D.C., District of Columbia
- Northwestern University โ Chicago, Illinois
- Centro Comprensivo de Cancer de UPR โ San Juan,
- University of Puerto Rico โ San Juan,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cirrhosis
- Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement โ Richmond, Virginia
- Liver Cirrhosis Network Cohort Study โ La Jolla, California
- Oral Health In Cirrhosis of the Liver (ORACLE) โ Richmond, Virginia
- Remote Electrical Stimulation for Pain and Depression Treatment in Cirrhosis โ Ann Arbor, Michigan
- Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis โ San Francisco, California
Explore by condition: All Cirrhosis clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.