๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-27

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis (NCT02968810)

Statin Therapy to Reduce Disease Progression From Liver Cirrhosis to Cancer

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: National Cancer Institute (NCI)

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This phase II trial studies how well simvastatin works in preventing liver cancer in patients with liver cirrhosis. Simvastatin may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.

Who can join: Review the eligibility criteria below.

Location: Cedars-Sinai Medical Center โ€” Los Angeles, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • Cedars-Sinai Medical Center โ€” Los Angeles, California
  • MedStar Georgetown University Hospital โ€” Washington D.C., District of Columbia
  • Northwestern University โ€” Chicago, Illinois
  • Centro Comprensivo de Cancer de UPR โ€” San Juan,
  • University of Puerto Rico โ€” San Juan,

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Cirrhosis clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—