A Study to Evaluate the Long-Term Efficacy and Safety of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 3) (NCT03519945)
A Phase 3, Multicenter, Open-Label Extension Study to Evaluate the Long Term Efficacy and Safety of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis LUCENT 3
🩺 Plain-English Summary (8th-Grade Level)
This study is designed to evaluate the long-term efficacy and safety of mirikizumab in participants with moderately to severely active ulcerative colitis (UC). The study will last up to 3 years. Participants who complete the 3-year study may continue to receive mirikizumab until it is (outside of this study) in their country or until they meet other discontinuation criteria.
Who can join: Review the eligibility criteria below.
Location: Digestive Health Specialists — Dothan, Alabama
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (352 Sites)
Showing the first 25 of 352 sites.
- Digestive Health Specialists — Dothan, Alabama
- Research Solutions of Arizona — Litchfield Park, Arizona
- Valleywise Health Medical Center — Phoenix, Arizona
- InSite Digestive Health Care — Arcadia, California
- Care Access - Berkeley — Berkeley, California
- Om Research LLC — Lancaster, California
- California Medical Research Associates — Northridge, California
- Inland Empire Clinical Trials, LLC — Rialto, California
- Clinical Applications Laboratories, Inc. — San Diego, California
- Direct Helpers Research Center — Hialeah, Florida
- Encore Borland-Groover Clinical Research — Jacksonville, Florida
- Wellness Clinical Research — Miami Lakes, Florida
- AdventHealth Orlando — Orlando, Florida
- Clintheory Healthcare — Orlando, Florida
- Gastroenterology Associates of Pensacola, PA — Pensacola, Florida
- Florida Medical Clinic LLC — Zephyrhills, Florida
- Digestive Healthcare of Georgia — Atlanta, Georgia
- Grand Teton Research Group — Idaho Falls, Idaho
- NorthShore University HealthSystem - Evanston Hospital — Evanston, Illinois
- Indiana University Health University Hospital — Indianapolis, Indiana
- Cotton O'Neil Digestive Health Center — Topeka, Kansas
- GI Alliance Research Baton Rouge — Baton Rouge, Louisiana
- Delta Research Partners — Monroe, Louisiana
- Nola Research Works, LLC — New Orleans, Louisiana
- University of Michigan — Ann Arbor, Michigan
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ulcerative Colitis
- A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001) — Dothan, Alabama
- Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis — San Diego, California
- A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Ulcerative Colitis and Their Infants — Eden Prairie, Minnesota
- CP101 for the Treatment of Ulcerative Colitis — Boston, Massachusetts
- A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis — Los Angeles, California
- Angiographic Delivery of AD-MSC for Ulcerative Colitis — Rochester, Minnesota
Explore by condition: All Ulcerative Colitis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.