๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-02-12

Reversal of Atrial Substrate to Prevent Atrial (NCT03682991)

Reversal of Atrial Substrate to Prevent Atrial Fibrillation

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿ“‹ Clinical Research Protocol Sponsor: Nova Scotia Health Authority

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.

Who can join: Review the eligibility criteria below.

Location: Foothills Hospital โ€” Calgary, Alberta

Age range: 18 Years

๐Ÿงช Interventions in This Study

  • Aggressive Risk Factor Control (OTHER)
  • Standard of Care (OTHER)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (17 Sites)

  • Foothills Hospital โ€” Calgary, Alberta
  • Mazankowski Alberta Heart Institute โ€” Edmonton, Alberta
  • Kelowna General Health โ€” Kelowna, British Columbia
  • St. Paul's Hospital โ€” Vancouver, British Columbia
  • Saint John Regional Hospital โ€” Saint John, New Brunswick
  • QE II Health Sciences Centre โ€” Halifax, Nova Scotia
  • Hamilton Health Sciences Center โ€” Hamilton, Ontario
  • St. Mary's General Hospital โ€” Kitchener, Ontario
  • London Health Sciences Center โ€” London, Ontario
  • Ottawa Heart Institute โ€” Ottawa, Ontario
  • St. Michael's Hospital โ€” Toronto, Ontario
  • Sunnybrook Health Sciences Centre โ€” Toronto, Ontario
  • Laval Hospital โ€” Laval, Quebec
  • McGill University Health Centre โ€” Montreal, Quebec
  • Montreal Heart Institute โ€” Montreal, Quebec
  • Sacre Coeur Hospital โ€” Montreal, Quebec
  • Regina General Hospital โ€” Regina, Saskatchewan

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—