๐๏ธ Verified NIH Record โข Updated 2026-02-12
Reversal of Atrial Substrate to Prevent Atrial (NCT03682991)
Reversal of Atrial Substrate to Prevent Atrial Fibrillation
๐ต Active, Not Recruiting Observational / Diagnostic ๐ Clinical Research Protocol Sponsor: Nova Scotia Health Authority
๐ฉบ Plain-English Summary (8th-Grade Level)
A multi-center, randomized trial to examine the effect of aggressive risk factor control and arrhythmia trigger-based intervention on recurrence of atrial fibrillation.
Who can join: Review the eligibility criteria below.
Location: Foothills Hospital โ Calgary, Alberta
Age range: 18 Years
๐งช Interventions in This Study
- Aggressive Risk Factor Control (OTHER)
- Standard of Care (OTHER)
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (17 Sites)
- Foothills Hospital โ Calgary, Alberta
- Mazankowski Alberta Heart Institute โ Edmonton, Alberta
- Kelowna General Health โ Kelowna, British Columbia
- St. Paul's Hospital โ Vancouver, British Columbia
- Saint John Regional Hospital โ Saint John, New Brunswick
- QE II Health Sciences Centre โ Halifax, Nova Scotia
- Hamilton Health Sciences Center โ Hamilton, Ontario
- St. Mary's General Hospital โ Kitchener, Ontario
- London Health Sciences Center โ London, Ontario
- Ottawa Heart Institute โ Ottawa, Ontario
- St. Michael's Hospital โ Toronto, Ontario
- Sunnybrook Health Sciences Centre โ Toronto, Ontario
- Laval Hospital โ Laval, Quebec
- McGill University Health Centre โ Montreal, Quebec
- Montreal Heart Institute โ Montreal, Quebec
- Sacre Coeur Hospital โ Montreal, Quebec
- Regina General Hospital โ Regina, Saskatchewan
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atrial Fibrillation
- CHAMPION-AF Clinical Trial โ Birmingham, Alabama
- Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients โ Rochester, New York
- REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry โ Chandler, Arizona
- Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF) โ Cleveland, Ohio
- Liraglutide Effect in Atrial Fibrillation โ Miami, Florida
Explore by condition: All Atrial Fibrillation clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.