๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-11

CHAMPION-AF Clinical Trial (NCT04394546)

WATCHMAN FLX Versus NOAC for Embolic ProtectION in in the Management of Patients With Non-Valvular Atrial Fibrillation

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Boston Scientific Corporation

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The primary objective of this study is to determine if left atrial appendage closure (LAAC) with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation.

Who can join: Review the eligibility criteria below.

Location: Grandview Medical Center โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (141 Sites)

Showing the first 25 of 141 sites.

  • Grandview Medical Center โ€” Birmingham, Alabama
  • University of Alabama at Birmingham โ€” Birmingham, Alabama
  • Arizona Arrhythmia Research Center โ€” Phoenix, Arizona
  • Phoenix Cardiovascular Research Group โ€” Phoenix, Arizona
  • Scottsdale Healthcare - Shea โ€” Scottsdale, Arizona
  • Tucson Medical Center Healthcare โ€” Tucson, Arizona
  • Arrythmia Research Group โ€” Jonesboro, Arkansas
  • Sharp Chula Vista Medical Center โ€” Chula Vista, California
  • Marin General Hospital โ€” Greenbrae, California
  • Scripps Memorial Hospital โ€” La Jolla, California
  • Los Robles Hospital and Medical Center โ€” Los Angeles, California
  • El Camino Hospital โ€” Mountain View, California
  • Eisenhower Medical Center โ€” Rancho Mirage, California
  • Mercy General Hospital โ€” Sacramento, California
  • Santa Barbara Cottage Hospital โ€” Santa Barbara, California
  • St. John's Health Center โ€” Santa Monica, California
  • Colorado Springs Cardiologist, P.C. โ€” Colorado Springs, Colorado
  • Yale University School of Medicine โ€” New Haven, Connecticut
  • Christiana Hospital โ€” Newark, Delaware
  • Washington Hospital Center โ€” Washington D.C., District of Columbia
  • Manatee Memorial Hospital โ€” Bradenton, Florida
  • Bay Area Cardiology Associates, P.A. โ€” Brandon, Florida
  • Broward General Medical Center โ€” Fort Lauderdale, Florida
  • St. Vincent's Medical Center โ€” Jacksonville, Florida
  • Lakeland Regional Medical Center โ€” Lakeland, Florida

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—