Extension Study for the Port Delivery System With Ranibizumab (Portal) (NCT03683251)
A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Portal)
🩺 Plain-English Summary (8th-Grade Level)
This study will evaluate the long-term safety and tolerability of the Port Delivery System with ranibizumab (PDS) (100 mg/mL) in participants with neovascular age-related macular degeneration (nAMD) who have either completed Phase II Study GX28228 (Ladder), Phase III Study GR40548 (Archway), Phase IIIb Study WR42221 (Velodrome), or completed Week 24 visit in Study WR42221 but were not eligible to be randomized in WR42221.
Who can join: Review the eligibility criteria below.
Location: Retinal Research Institute, LLC — Phoenix, Arizona
Age range: 50 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (165 Sites)
Showing the first 25 of 165 sites.
- Retinal Research Institute, LLC — Phoenix, Arizona
- Arizona Retina and Vitreous Consultants — Phoenix, Arizona
- Barnet Dulaney Perkins Eye Center — Phoenix, Arizona
- Associated Retina Consultants — Phoenix, Arizona
- Retinal Consultants of Arizona — Phoenix, Arizona
- California Retina Consultants — Bakersfield, California
- Retina-Vitreous Associates Medical Group — Beverly Hills, California
- The Retina Partners — Encino, California
- Jacobs Retina center at the Shiley eye Institute UCSD — La Jolla, California
- Jules Stein Eye Institute/ UCLA — Los Angeles, California
- N CA Retina Vitreous Assoc — Mountain View, California
- Retina Consultants, San Diego — Poway, California
- Retinal Consultants Med Group — Sacramento, California
- West Coast Retina Medical Group — San Francisco, California
- UCSF — San Francisco, California
- Orange County Retina Med Group — Santa Ana, California
- California Retina Consultants — Santa Barbara, California
- Southwest Retina Consultants — Durango, Colorado
- Eye Center of Northern CO — Fort Collins, Colorado
- Colorado Retina Associates, PC — Lakewood, Colorado
- Retina Group of New England — Waterford, Connecticut
- Florida Eye Microsurgical Inst — Boynton Beach, Florida
- National Ophthalmic Research Institute — Fort Myers, Florida
- Florida Eye Associates — Melbourne, Florida
- Retina Care Specialists — Palm Beach Gardens, Florida
📞 Contact the Study Coordinator
Phone: (888) 662-6728
Email: global-roche-genentech-trials@gene.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Neovascular Age-Related Macular Degeneration
- A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME) — Arcadia, California
- A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration — Phoenix, Arizona
- Effect of AIV007 by Periocular Administration in Subjects with Macular Edema Secondary to Neovascular Age-related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) — Beverly Hills, California
- Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration — Gilbert, Arizona
- Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD — Glendale, California
- Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA] — Phoenix, Arizona
Explore by condition: All Neovascular Age-Related Macular Degeneration clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.