๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-05

Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated Glioblastoma (NCT03743662)

A Phase II Trial of the PD-1 Antibody Nivolumab in Combination With Hypofractionated Re-irradiation and Bevacizumab for Recurrent MGMT Methylated Glioblastoma

๐Ÿ”ต Active, Not Recruiting Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Memorial Sloan Kettering Cancer Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study is being done to see if adding nivolumab to radiation therapy and bevacizumab can increase the effectiveness of the treatment for recurrent glioblastoma.

Who can join: Review the eligibility criteria below.

Location: Hartford Healthcare (Data Collection) โ€” Hartford, Connecticut

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (11 Sites)

  • Hartford Healthcare (Data Collection) โ€” Hartford, Connecticut
  • Indiana University (Data Collection Only) โ€” Indianapolis, Indiana
  • Memorial Sloan Kettering Basking Ridge โ€” Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth โ€” Middletown, New Jersey
  • Memorial Sloan Kettering Bergen โ€” Montvale, New Jersey
  • Memorial Sloan Kettering Commack โ€” Commack, New York
  • Memorial Sloan Kettering Westchester โ€” Harrison, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • Memorial Sloan Kettering Nassau โ€” Uniondale, New York
  • Lehigh Valley Health Network (Data Collection Only) โ€” Allentown, Pennsylvania
  • University of Vermont Medical Center (Data Collection Only) โ€” Burlington, Vermont

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Glioblastoma clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—