Collagen Cross-linking in Keratoconus (NCT03760432)
Clinical Trial of Laser Custom Corneal Collagen Cross-Linking in Keratoconus
🩺 Plain-English Summary (8th-Grade Level)
Optical Coherence Tomography (OCT) devices are non-contact instruments that can measure the depth of scars, other causes of cloudiness of the cornea, and degree of corneal thinning in patients with keratoconus. Laser Custom Corneal Collagen Cross-linking (CXL) significantly decreases corneal aberrations and improves vision. This study will use OCT-guided setting for the lasers used in the corneal smoothing portion of the laser custom CXL procedure to assess the affect on visual outcomes.
Who can join: Review the eligibility criteria below.
Location: Oregon Health & Science University — Portland, Oregon
Age range: 18 Years
🧪 Interventions in This Study
- Laser Custom Corneal Collagen Cross-Linking (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Oregon Health & Science University — Portland, Oregon
📞 Contact the Study Coordinator
Phone: (503) 494-4351
Email: romfhd@ohsu.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Keratoconus
- Initial Correction Keratoconus — Chicago, Illinois
- McNeel Eye Center Corneal Crosslinking Study — Boise, Idaho
- Assessing Patient Engagement in Keratoconus Clinical Research — San Francisco, California
- Outcomes of CTAK Surgery — Palo Alto, California
- A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients — Boston, Massachusetts
- OCT in Diagnosis of Irregular Corneas — Portland, Oregon
Explore by condition: All Keratoconus clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.