A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma (NCT03778957)
A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Transarterial Chemoembolization (TACE) in Combination With Either Durvalumab Monotherapy or Durvalumab Plus Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma (EMERALD-1)
๐ฉบ Plain-English Summary (8th-Grade Level)
A global study to evaluate transarterial chemoembolization (TACE) in combination with durvalumab and bevacizumab therapy in patients with locoregional hepatocellular carcinoma
Who can join: Review the eligibility criteria below.
Location: Research Site โ Costa Mesa, California
Age range: 18 Years to 110 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (166 Sites)
Showing the first 25 of 166 sites.
- Research Site โ Costa Mesa, California
- Research Site โ La Jolla, California
- Research Site โ Orange, California
- Research Site โ Washington D.C., District of Columbia
- Research Site โ Jacksonville, Florida
- Research Site โ Miami, Florida
- Research Site โ Honolulu, Hawaii
- Research Site โ Chicago, Illinois
- Research Site โ Shreveport, Louisiana
- Research Site โ Detroit, Michigan
- Research Site โ Rochester, Minnesota
- Research Site โ St Louis, Missouri
- Research Site โ Stony Brook, New York
- Research Site โ Charlotte, North Carolina
- Research Site โ Cleveland, Ohio
- Research Site โ Portland, Oregon
- Research Site โ Pittsburgh, Pennsylvania
- Research Site โ Sioux Falls, South Dakota
- Research Site โ Memphis, Tennessee
- Research Site โ Dallas, Texas
- Research Site โ Dallas, Texas
- Research Site โ Houston, Texas
- Research Site โ Houston, Texas
- Research Site โ Milwaukee, Wisconsin
- Research Site โ Benowa,
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Hepatocellular Carcinoma
- TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients โ Maywood, Illinois
- Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab โ San Diego, California
- Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC) โ Baltimore, Maryland
- TheraSphere With Durvalumab and Tremelimumab for HCC โ San Diego, California
- Blood Salvage in Orthotopic Liver Transplantation With HCC โ Toronto, Ontario
- Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC) โ Prescott Valley, Arizona
Explore by condition: All Hepatocellular Carcinoma clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.