Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (NCT03901807)

🧪 Interventions in This Study

• Toraymyxin PMX 20R Extracorporeal Hemoperfusion Cartridge (DEVICE)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (20 Sites)

• University of Alabama at Birmingham — Birmingham, Alabama
• University of Arkansas for Medical Sciences — Little Rock, Arkansas
• University of California, San Francisco — San Francisco, California
• Pulmonary Associates — Boulder, Colorado
• George Washington University — Washington D.C., District of Columbia
• Emory University — Atlanta, Georgia
• Louisiana State University Health Shreveport — Shreveport, Louisiana
• Baystate Medical Center — Springfield, Massachusetts
• University of Michigan — Ann Arbor, Michigan
• Mayo Clinic — Rochester, Minnesota
• Cooper Health System — Camden, New Jersey
• Rutgers, The State University of New Jersey — Piscataway, New Jersey
• Mt Sinai Hospital — New York, New York
• Stony Brook University — Stony Brook, New York
• UPMC — Pittsburgh, Pennsylvania
• Medical University of South Carolina — Charleston, South Carolina
• CHI Memorial — Chattanooga, Tennessee
• Parkridge Hospital — Chattanooga, Tennessee
• The University of Texas Health Science Center at Houston — Houston, Texas
• Institute for Extracorporeal Life Support — San Antonio, Texas

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

More studies in Septic Shock

• Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance — Cleveland, Ohio
• Blood Purification for the Treatment of Pathogen Associated Shock — Washington D.C., District of Columbia
• Venous Excess Ultrasound for Personalized Resuscitation in Septic Shock — London, Ontario
• Evaluating Dynamic Arterial Elastance in Septic Shock Patients. — Bogotá,
• Randomized Control Study in REsuscitation of SEpsis Trial — Bogotá, Bogota D.C.

Explore by condition: All Septic Shock clinical trials

💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Review the official NIH record below to find the coordinating site.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.