An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis (NCT03950232)
An Open-Label Extension Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blind treatment (either etrasimod 2 mg per day or placebo) during participation in one of the qualified Phase 3 or Phase 2 double-blind, placebo-controlled parent studies including but not limited to: (APD334-301 \[NCT03945188\] or APD334-302 \[NCT03996369\] or APD334-210 \[NCT04607837\]).
Who can join: Review the eligibility criteria below.
Location: Center for Digestive Health (Colonoscopy Location) — Dothan, Alabama
Age range: 16 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (470 Sites)
Showing the first 25 of 470 sites.
- Center for Digestive Health (Colonoscopy Location) — Dothan, Alabama
- Digestive Health Specialists (IP Address) — Dothan, Alabama
- Flowers Hospital (PFT Location) — Dothan, Alabama
- Pulmonary Associates (Secondary PFT Location) — Dothan, Alabama
- Gut P.C., dba Digestive Health Specialists of the Southeast (IP Address) — Dothan, Alabama
- Inland Pulmonary Specialists [PFT Only] — Lake Elsinore, California
- A V Pediatrics,Allergy and Family Medicine — Lancaster, California
- Advanced Endoscopy and Pain Center(Colonoscopy) — Lancaster, California
- Antelope Valley Eye Care(Ophthalmologist) — Lancaster, California
- Jatinder S.Pruthi,MD FACG CPI — Lancaster, California
- Om Research LLC — Lancaster, California
- Renaissance Imaging Center(Chest X-Ray only) — Lancaster, California
- United Surgery Center Murrieta [Endoscopy Only] — Murrieta, California
- United Medical Doctors — Murrieta, California
- Advanced Imaging (Chest X-Ray) — Palmdale, California
- California Eye Professionals [OCT Only] — Temecula, California
- United Surgery Center Temecula [Endoscopy Only] — Temecula, California
- Front Range Endoscopy Center — Colorado Springs, Colorado
- Peak Gastroenterology Associates — Colorado Springs, Colorado
- Bay Area Chest Physicians, P.A.,-(Pulmonary Function Test) — Clearwater, Florida
- West Coast Endoscopy Center (Endoscopy Procedures) — Clearwater, Florida
- Northwood Vision- Optical Coherence Tomography (OCT) — Clearwater, Florida
- Northwood Vision-Optical Coherence Tomography-(OCT) — Clearwater, Florida
- Safety Harbor Surgery (Endoscopy Facility) — Clearwater, Florida
- Gastro Florida (Regulatory & Administrative Duties) — Clearwater, Florida
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ulcerative Colitis
- A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001) — Dothan, Alabama
- Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis — San Diego, California
- A Study to Evaluate the Safety of Ozanimod Exposure During Pregnancy in Women With Ulcerative Colitis and Their Infants — Eden Prairie, Minnesota
- CP101 for the Treatment of Ulcerative Colitis — Boston, Massachusetts
- A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis — Los Angeles, California
- Angiographic Delivery of AD-MSC for Ulcerative Colitis — Rochester, Minnesota
Explore by condition: All Ulcerative Colitis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.