Comparing Uni- and Bi-lateral TBS in Major Depression (NCT04142996)
A Naturalistic Study Comparing Uni- and Bi-lateral Theta Burst Stimulation in Major Depression
🩺 Plain-English Summary (8th-Grade Level)
Repetitive transcranial magnetic stimulation (rTMS) is a Health Canada approved treatment for major depression. Theta burst stimulation (TBS) is a very promising new treatment for major depression that allows a 15-fold reduction in duration of daily sessions. However, no large scale naturalistic study has assessed the superiority of bilateral TBS in comparison with unilateral left TBS. In fact, no TBS study thus far has included both unipolar and bipolar depression, or other psychiatric comorbidities such as anxiety. Maintenance has yet to be studied with TBS, along with an effective maintenance protocol to prevent relapse. Our study aims to explore and address these gaps.
Who can join: Review the eligibility criteria below.
Location: The Royal Ottawa Mental Health Centre — Ottawa, Ontario
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- The Royal Ottawa Mental Health Centre — Ottawa, Ontario
📞 Contact the Study Coordinator
Phone: (613) 722-6521
Email: stacey.shim@theroyal.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Major Depressive Episode
- Personalized Ultrasonic Brain Stimulation for Depression — Salt Lake City, Utah
- Patient-oriented Randomized Pragmatic Feasibility Trial With rTMS in Depression and Anxiety — Vancouver, British Columbia
- Personalized Ultrasonic Brain Stimulation for Depression (R61) — Salt Lake City, Utah
- The Impact of Coach-guided Risk Communication on the Risk of Major Depression — Halifax, Nova Scotia
Explore by condition: All Major Depressive Episode clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.