Personalized Ultrasonic Brain Stimulation for Depression (NCT05301036)
Personalized Ultrasonic Brain Stimulation for Depression: A Pilot Study of Target Engagement and Mood Effects
🩺 Plain-English Summary (8th-Grade Level)
This study will evaluate a new form of non-invasive brain stimulation for individuals with depression. Personalized low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychological and physiological monitoring. A well-tolerated stimulation protocol will then be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial to evaluate brain target engagement using magnetic resonance imaging.
Who can join: Review the eligibility criteria below.
Location: University of Utah — Salt Lake City, Utah
Age range: 18 Years to 65 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- University of Utah — Salt Lake City, Utah
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Major Depressive Episode
- Patient-oriented Randomized Pragmatic Feasibility Trial With rTMS in Depression and Anxiety — Vancouver, British Columbia
- Personalized Ultrasonic Brain Stimulation for Depression (R61) — Salt Lake City, Utah
- The Impact of Coach-guided Risk Communication on the Risk of Major Depression — Halifax, Nova Scotia
- Comparing Uni- and Bi-lateral TBS in Major Depression — Ottawa, Ontario
Explore by condition: All Major Depressive Episode clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.