๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-01

Trifecta-Kidney cfDNA-MMDx Study (NCT04239703)

Trifecta-Kidney cfDNA-MMDx Study: Comparing the DD-cfDNA Test to MMDx Microarray Test, Central HLA Antibody Test, and Histology.

๐ŸŸข Recruiting Interventional Protocol ๐Ÿ“Š Observational Clinical Research Sponsor: University of Alberta

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscopeยฎ (MMDx) Diagnostic System results in indication biopsies.

Who can join: Review the eligibility criteria below.

Location: Tampa General Hospital โ€” Tampa, Florida

๐Ÿงช Interventions in This Study

  • MMDx (DIAGNOSTIC_TEST)
  • Prospera (DIAGNOSTIC_TEST)
  • HLA antibody (DIAGNOSTIC_TEST)

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (31 Sites)

Showing the first 25 of 31 sites.

  • Tampa General Hospital โ€” Tampa, Florida
  • University of Maryland School of Medicine โ€” Baltimore, Maryland
  • The Johns Hopkins University, School of Medicine โ€” Baltimore, Maryland
  • Detroit Medical Center, Harper University Hospital of Wayne State University โ€” Detroit, Michigan
  • Henry Ford Hospital โ€” Detroit, Michigan
  • Barnes-Jewish Hospital, Washington University at St. Louis โ€” St Louis, Missouri
  • University Hospitals Cleveland Medical Ctr. โ€” Cleveland, Ohio
  • Cleveland Clinic โ€” Cleveland, Ohio
  • Intermountain Transplant Services โ€” Murray, Utah
  • Virginia Commonwealth University Medical Center โ€” Richmond, Virginia
  • Division of Nephrology & UW Organ Transplant Center University of Washington โ€” Seattle, Washington
  • Department of Nephrology, The Royal Melbourne Hospital 1 South East โ€” Melbourne,
  • University of Alberta, Department of Medicine โ€” Edmonton, Alberta
  • ST. Paul's Hospital, 6A Providence Building, 1081 Burrard Street โ€” Vancouver, British Columbia
  • University Hospital Merkur Renal Division โ€” Zagreb,
  • Institute for Clinical and Experimental Medicine (IKEM) โ€” Prague,
  • Charite-Medical University of Berlin Department of Nephrology โ€” Berlin,
  • Centre of Nephrology, Vilnius University Hospital Santaros Klinikos โ€” Vilnius,
  • Department of Nephrology and Transplantation Medical University in Bialystok โ€” Bialystok,
  • University Hospital nr1 Bydgoszcz, Klinika Transplantologii โ€” Bydgoszcz,
  • Medical University of Gdaล„sk Klinika Nefrologii Transplantologii i Chorรณb Wewnฤ™trznych โ€” Gdansk,
  • Medical University of Silesia โ€” Katowice,
  • Department of Transplantation and General Surgery, Wojewodzki Hospital โ€” Poznan,
  • Department of Nephrology, Transplantation and Internal Medicine, University Hospital n.2 โ€” Szczecin,
  • Pomeranian Medical University, Samodzielny Publiczny Woj. Szpital Zespolony, Oddzial Nefrologii i Transplantacji Nerek โ€” Szczecin,

๐Ÿ“ž Contact the Study Coordinator

Phone: (780) 492-1725

Email: konrad@ualberta.ca

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—