🏛️ Verified NIH Record • Updated 2025-04-18
Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis (NCT04440189)
Use of GID SVF-2 Device to Produce Autologous Adipose-Derived Stromal Vascular Fraction for Treatment of Osteoarthritis of the Knee: A Pivotal Medical Device Randomized Concurrent Controlled Study
🔵 Active, Not Recruiting Phase3 ⚙️ Medical Device Protocol Sponsor: GID BIO, Inc.
🩺 Plain-English Summary (8th-Grade Level)
This is a pivotal study to evaluate the efficacy and safety of a single injection of autologous adipose-derived SVF produced using the GID SVF-2 device system for treatment of pain with concomitant improvement in function associated with osteoarthritis of the knee joint.
Who can join: Review the eligibility criteria below.
Location: UC Davis — Sacramento, California
Age range: 35 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (9 Sites)
- UC Davis — Sacramento, California
- Advanced Research LLC — Coral Springs, Florida
- Tulane University — New Orleans, Louisiana
- New Jersey Regenerative Institute — Cedar Knolls, New Jersey
- OrthoCarolina Research Institute — Charlotte, North Carolina
- Wake Forest University Health Sciences — Winston-Salem, North Carolina
- Ohio State University Jameson Crane Sports Medicine Institute — Columbus, Ohio
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- Texas Center for Cell Therapy and Research — San Antonio, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Osteoarthritis, Knee
- The Impact of Procedural Awareness of Knee Injections for Osteoarthritis on Patient Perceptions of Effectiveness — Hamilton, Ontario
- Genicular Radiofrequency Ablation Following Total Knee Arthroplasty — Calgary, Alberta
- Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain — Tempe, Arizona
- Prospective Randomized Study of Cementless vs Cemented UKA — New Albany, Ohio
- Clinical Outcomes of Joint Arthroplasty — St. Helena, California
Explore by condition: All Osteoarthritis, Knee clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.