🏛️ Verified NIH Record • Updated 2026-08-10
A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS) (NCT04631406)
A Phase 1/Phase 2a Safety and Tolerability Study of Intracerebral Transplantation of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS) and Early Evaluation of Potentially Useful Efficacy Parameters
🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic Sponsor: Clarion Cells, Inc.
🩺 Plain-English Summary (8th-Grade Level)
Evaluation of the safety and tolerability of escalating doses of NR1 administered intracerebrally at a single time-point post-injury to subjects with chronic ISS with or without cortical stroke.
Who can join: Review the eligibility criteria below.
Location: Stanford Health Center — Stanford, California
Age range: 18 Years to 75 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (1 Sites)
- Stanford Health Center — Stanford, California
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ischemic Stroke
- OsciPulse D-dimer Pilot Trial — Philadelphia, Pennsylvania
- Memantine for Enhanced Stroke Recovery — Salt Lake City, Utah
- Sleep for Stroke Management and Recovery Trial — Birmingham, Alabama
- Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial — Huntsville, Alabama
- VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home — Chicago, Illinois
Explore by condition: All Ischemic Stroke clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.