๐๏ธ Verified NIH Record โข Updated 2026-07-17
Defibrotide for the Treatment of Severe COVID-19 (NCT04652115)
A Single-Arm Safety and Feasibility Study of Defibrotide for the Treatment of Severe COVID-19
๐ข Recruiting Phase2 ๐ Investigational Drug / Biologic Sponsor: Brigham and Women's Hospital
๐ฉบ Plain-English Summary (8th-Grade Level)
The goal of this study is to evaluate the safety and feasibility of defibrotide in COVID-19 pneumonia.
Who can join: Review the eligibility criteria below.
Location: Brigham and Women's Hospital โ Boston, Massachusetts
Age range: 18 Years to 100 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (1 Sites)
- Brigham and Women's Hospital โ Boston, Massachusetts
๐ Contact the Study Coordinator
Phone: (617) 632-2127
Email: Paul_Richardson@dfci.harvard.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Covid19
- Pediatric COVID Outcomes Study (PECOS) โ Washington D.C., District of Columbia
- SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival โ Edmonton, Alberta
- COVID-FISETIN: Pilot in SARS-CoV-2 of Fisetin to Alleviate Dysfunction and Inflammation โ Rochester, Minnesota
- The Canadian COVID-19 Prospective Cohort Study โ Calgary, Alberta
- Post Acute Sequelae of COVID-19 โ Nashville, Tennessee
- Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection โ Hamilton, Ontario
Explore by condition: All Covid19 clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.