Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway (NCT04744298)
Identification and Treatment of Hypoxemic Respiratory Failure (HRF) and ARDS With Protection, Paralysis, and Proning: TheraPPP Study
🩺 Plain-English Summary (8th-Grade Level)
Treatment of patients with Hypoxemic respiratory failure (HRF) and Acute Respiratory Distress Syndrome (ARDS) is complex. Therapies that have been shown to save the lives of patients with HRF and ARDS are available but they are not always provided. To reduce practice variation and improve adherence to evidence-informed therapies, the investigators developed the Treatment of Hypoxemic Respiratory Failure and ARDS with Protection, Paralysis, and Proning (TheraPPP) Pathway. The overall objective of TheraPPP Pathway is to improve the quality of care for patients with HRF. Implementation of the pathway across Alberta will test the effectiveness and implementation of the TheraPPP Pathway.
Who can join: Review the eligibility criteria below.
Location: Peter Lougheed Centre (PLC) — Calgary, Alberta
Age range: 18 Years
🧪 Interventions in This Study
- TheraPPP (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (17 Sites)
- Peter Lougheed Centre (PLC) — Calgary, Alberta
- Foothills Hospital Intensive Care Unit — Calgary, Alberta
- Foothills Medical Center Cardiovascular ICU — Calgary, Alberta
- Rockyview General Hospital — Calgary, Alberta
- South Health Campus — Calgary, Alberta
- Royal Alexandra Hospital — Edmonton, Alberta
- Misericordia Community Hospital — Edmonton, Alberta
- Mazankowski Alberta Heart Institute — Edmonton, Alberta
- University of Alberta Hospital General Systems ICU — Edmonton, Alberta
- University of Alberta Hospital Neurosciences Intensive Care Unit — Edmonton, Alberta
- Grey Nuns Community Hospital — Edmonton, Alberta
- Northern Lights Regional Health Centre — Fort McMurray, Alberta
- Queen Elizabeth II Hospital — Grande Prairie, Alberta
- Chinook Regional Hospital — Lethbridge, Alberta
- Medicine Hat Regional Hospital — Medicine Hat, Alberta
- Red Deer Regional Hospital Centre — Red Deer, Alberta
- Sturgeon Community Hospital — St. Albert, Alberta
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Respiratory Distress Syndrome
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- Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome — Tucson, Arizona
- Macrophage Programing in Acute Lung Injury: MiniBAL — Denver, Colorado
- Vascular ARDS Recruitment After Inhaled Nitric Oxide — Boston, Massachusetts
Explore by condition: All Acute Respiratory Distress Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.