Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome (NCT06066502)
PREcision VENTilation to Attenuate Ventilator-Induced Lung Injury: A Phase 3 Multicenter Randomized Clinical Trial
🩺 Plain-English Summary (8th-Grade Level)
The goal of this interventional study is to compare standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with Acute Respiratory Distress Syndrome (ARDS). Participants will be ventilated according to one of two different strategies. The main question the study hopes to answer is whether the personalized ventilation strategy helps improve survival.
Who can join: Review the eligibility criteria below.
Location: University of Arizona — Tucson, Arizona
Age range: 18 Years
🧪 Interventions in This Study
- Precision ventilation (OTHER)
- Guided usual care ventilation (OTHER)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (33 Sites)
Showing the first 25 of 33 sites.
- University of Arizona — Tucson, Arizona
- University of Arkansas for Medical Sciences — Little Rock, Arkansas
- University of California, San Diego — La Jolla, California
- University of California, Los Angeles Medical Center — Los Angeles, California
- Cedar-Sinai Medical Center — Los Angeles, California
- Stanford University — Palo Alto, California
- University of California, San Francisco — San Franciso, California
- University of Miami — Miami, Florida
- Emory University / Grady Health System — Atlanta, Georgia
- University of Chicago — Chicago, Illinois
- Tufts Medical Center — Boston, Massachusetts
- Massachusetts General Hospital — Boston, Massachusetts
- Brigham and Women's Hospital — Boston, Massachusetts
- Beth Israel Deaconess Medical Center — Boston, Massachusetts
- Lowell General Hospital — Lowell, Massachusetts
- University of Michigan — Ann Arbor, Michigan
- Mayo Clinic — Rochester, Minnesota
- NYU Lagone Health — New York, New York
- New York City Health + Hospitals/ Bellevue — New York, New York
- Albert Einstein College of Medicine/Montefiore Medical Center — The Bronx, New York
- Duke University Medical Center — Durham, North Carolina
- Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina
- University of Cincinnati — Cincinnati, Ohio
- Cleveland Clinic Foundation — Cleveland, Ohio
- Ohio State University Wexner Medical Center — Columbus, Ohio
📞 Contact the Study Coordinator
Phone: (617) 632-8055
Email: vgoodspe@bidmc.harvad.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Acute Respiratory Distress Syndrome
- Identification and Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning Pathway — Calgary, Alberta
- Molecular Epidemiology of Acute Respiratory Distress Syndrome (ARDS) — Boston, Massachusetts
- ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND) — Birmingham, Alabama
- Macrophage Programing in Acute Lung Injury: MiniBAL — Denver, Colorado
- Vascular ARDS Recruitment After Inhaled Nitric Oxide — Boston, Massachusetts
Explore by condition: All Acute Respiratory Distress Syndrome clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.