AERIAL Trial: Antiplatelet Therapy in Heart Transplantation (NCT04770012)
Early Initiation of Antiplatelet ThERapy In HeArt TranspLantation: AERIAL Trial
🩺 Plain-English Summary (8th-Grade Level)
Cardiac allograft vasculopathy is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. The research team is investigating whether early antiplatelet therapy post heart transplant can prevent the development of CAV. This study will determine the feasibility of a large multicenter randomized placebo-controlled trial to answer this question.
Who can join: Review the eligibility criteria below.
Location: St.Pauls Hospital — Vancouver, British Columbia
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (3 Sites)
- St.Pauls Hospital — Vancouver, British Columbia
- University of Ottawa Heart Institute — Ottawa, Ontario
- Toronto General Hospital UHN — Toronto, Ontario
📞 Contact the Study Coordinator
Phone: (613) 696-7000
Email: schih@ottawaheart.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiac Allograft Vasculopathy
- Early Post Transplant Cardiac Allograft Vasculopathy — Ottawa, Ontario
- MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation — Calgary, Alberta
Explore by condition: All Cardiac Allograft Vasculopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.