MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation (NCT06089486)
Multiparametric Cardiac Positron Emission Tomography for Cardiac Allograft Vasculopathy Surveillance After Heart Transplantation
🩺 Plain-English Summary (8th-Grade Level)
Cardiac allograft vasculopathy (CAV) is a common complication affecting heart transplant patients. This condition causes narrowing of the heart arteries leading to graft dysfunction. Surveillance for CAV is vital; however an ideal approach has not been established. The goal of this study is to assess whether noninvasive positron emission tomography (PET) based surveillance is non-inferior to invasive coronary angiography (ICA) surveillance.
Who can join: Review the eligibility criteria below.
Location: University of Calgary — Calgary, Alberta
Age range: 18 Years
🧪 Interventions in This Study
- ICA (DIAGNOSTIC_TEST)
- PET (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (5 Sites)
- University of Calgary — Calgary, Alberta
- Mazankowski Alberta Heart Institute — Edmonton, Alberta
- University of Ottawa Heart Institute — Ottawa, Ontario
- Toronto-General Hospital - University Health Network — Toronto, Ontario
- Montreal Heart Institute — Montreal, Quebec
📞 Contact the Study Coordinator
Phone: (613) 696-7000
Email: schih@ottawaheart.ca
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Cardiac Allograft Vasculopathy
- Early Post Transplant Cardiac Allograft Vasculopathy — Ottawa, Ontario
- AERIAL Trial: Antiplatelet Therapy in Heart Transplantation — Vancouver, British Columbia
Explore by condition: All Cardiac Allograft Vasculopathy clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.