๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-07

A Study Assessing Corneal Endothelial Cells in Participants With Neovascular Age-related Macular Degeneration (nAMD) Treated With the Port Delivery System With Ranibizumab (PDS) (NCT04853251)

A Phase IV, Multicenter, Open-label Study to Assess Corneal Endothelial Cells in Patients With Neovascular Age-related Macular Degeneration Treated With the Port Delivery System With Ranibizumab (PDS)

๐ŸŸข Recruiting Phase4 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Genentech, Inc.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study will assess corneal endothelial cells in participants with nAMD treated with PDS refilled every 24 weeks (Q24W).

Who can join: Review the eligibility criteria below.

Location: Barnet Dulaney Perkins Eye Center โ€” Mesa, Arizona

Age range: 50 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (52 Sites)

Showing the first 25 of 52 sites.

  • Barnet Dulaney Perkins Eye Center โ€” Mesa, Arizona
  • California Retina Consultants โ€” Bakersfield, California
  • Retina Associates of Southern California โ€” Huntington Beach, California
  • California Eye Specialists Medical group Inc. โ€” Pasadena, California
  • Retinal Consultants Med Group โ€” Sacramento, California
  • University of California San Francisco โ€” San Francisco, California
  • Orange County Retina Med Group โ€” Santa Ana, California
  • Macula Retina Vitreous Research Institute โ€” Torrance, California
  • Southwest Retina Consultants โ€” Durango, Colorado
  • Advanced Vision Research Institute โ€” Longmont, Colorado
  • Retina Group of New England โ€” Waterford, Connecticut
  • Retina Specialty Institute โ€” Pensacola, Florida
  • Ft Lauderdale Eye Institute โ€” Plantation, Florida
  • Retina Vitreous Associates of Florida โ€” St. Petersburg, Florida
  • Southeast Retina Center โ€” Augusta, Georgia
  • University Retina and Macula Associates, PC โ€” Lemont, Illinois
  • Wolfe Eye Clinic โ€” West Des Moines, Iowa
  • Retina Associates of Kentucky โ€” Lexington, Kentucky
  • Maine Eye Center โ€” Portland, Maine
  • The Retina Care Center โ€” Baltimore, Maryland
  • Wilmer Eye Institute Johns Hopkins University โ€” Baltimore, Maryland
  • Retina Group of Washington โ€” Chevy Chase, Maryland
  • Cumberland Valley Retina Consultants PC โ€” Hagerstown, Maryland
  • Associated Retinal Consultants PC โ€” Royal Oak, Michigan
  • VitreoRetinal Surgery, PLLC. โ€” Minneapolis, Minnesota

๐Ÿ“ž Contact the Study Coordinator

Phone: (888) 662-6728

Email: global-roche-genentech-trials@gene.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—