Detecting HPV DNA in Anal and Cervical Cancers (NCT04857528)
Circulating HPV DNA in Cancers of the Anus and Uterine Cervix Treated With Definitive Radiation Therapy
🩺 Plain-English Summary (8th-Grade Level)
This is a research study for individuals who have cancer associated with human papillomavirus (HPV) and are being treated with radiation as part of standard care for their cancer. Doctors leading this study will use blood tests to find out if they can detect the HPV virus in the blood of study participants before, during, and after radiation treatment. They will also collect blood and archival tumor tissue (from a previous biopsy) to perform other tests in the future that could provide more information about HPV-associated cancers and how they respond to treatment. Participation in this study will last approximately 2 years.
Who can join: Review the eligibility criteria below.
Location: University of Illinois at Chicago — Chicago, Illinois
Age range: 18 Years
🧪 Interventions in This Study
- Radiation Treatment With or Without Chemotherapy (RADIATION)
- Blood Sample Collection (OTHER)
- HPV Genotyping (HPV DNA Test) (DIAGNOSTIC_TEST)
- Testing Archival Tumor Tissue (DIAGNOSTIC_TEST)
- Physical Exam (OTHER)
- Positron Emission Tomography Scan (PET Scan)/ Computed Tomography Scan (CT Scan) (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- University of Illinois at Chicago — Chicago, Illinois
- University of Chicago — Chicago, Illinois
📞 Contact the Study Coordinator
Phone: (773) 702-6870
Email: cson@radonc.uchicago.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.