GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC (NCT04864054)
An Open-Label, Dose Escalation, Multi-Center Phase I/II Clinical Trial of ECT204 T-Cell Therapy in Adults With Advanced Hepatocellular Carcinoma (HCC)
🩺 Plain-English Summary (8th-Grade Level)
This is an open-label, multi-center, Phase 1/2 clinical trial evaluating the safety, tolerability, and efficacy of ECT204, an investigational ARTEMIS® T-cell therapy, in adult subjects with GPC3-positive hepatocellular carcinoma (HCC) who have experienced disease progression on, or intolerance to, prior systemic therapy.
Who can join: Review the eligibility criteria below.
Location: City of Hope — Duarte, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (8 Sites)
- City of Hope — Duarte, California
- Kansas University Medical Center, Principal Investigator: — Westwood, Kansas
- Roswell Park Comprehensive Cancer Center — Buffalo, New York
- Montefiore Einstein Comprehensive Cancer Center — The Bronx, New York
- Oregon Health and Sciences University — Portland, Oregon
- University of Texas Southwestern, Harold C. Simmons Comprehensive Cancer Center — Dallas, Texas
- Fred Hutchinson Cancer Center, University of Washington — Seattle, Washington
- National Taiwan University Cancer Center — Taipei,
📞 Contact the Study Coordinator
Phone: (925) 949-9314
Email: Teresa.Klask@eurekainc.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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Explore by condition: All Hepatocellular Carcinoma clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.